Progressive viral-induced cirrhosis: serial MR imaging findings and clinical correlation.

Abstract

Progressive atrophy of the right hepatic lobe and the medial segment correlated with progression of clinical severity of cirrhosis, whereas increasing size of the caudate lobe and the lateral segment correlated with stability.

Morphometric changes in liver cirrhosis: aetiological differences correlated with progression

“…However, as cirrhosis progresses, the characteristic histological features of various aetiologies may be lost, and the features of specific types of cirrhosis may become indistinguishable from cirrhosis owing to other causes. 29 In addition, the hypertrophic area cannot compensate for the atrophic area, and the whole liver eventually shows atrophy in advanced cirrhosis as shown previously [5][6][7] and in our study. Therefore, the magnitude of the differences between aetiologies would decrease with progression of cirrhosis as shown in our study, although there were no baseline scans of the patients in different stages of cirrhosis.…”

“…For the objective evaluation of these morphometric changes, conventional cross-sectional imaging by multidetector CT (MDCT) or MR imaging is essential. [5][6][7][8][9][10][11][12][13][14] Furthermore, recent advances in MDCT have made it possible to obtain rapid volumetric scanning and three-dimensional reconstruction and provided a new method for precisely measuring liver volume and evaluating intrahepatic vascular structures. 6,7 Morphometric changes of liver cirrhosis on imaging commonly include atrophy of the medial segment and right lobe and hypertrophy of the lateral segment and caudate lobe.…”

“…[8][9][10][11][12][13][14] In addition to differences related to the underlying aetiology, morphometric changes may also depend on the progression of cirrhosis. 5 The purpose of this study was to evaluate the morphometric changes in liver cirrhosis using MDCT volumetry and to analyse the differences in morphometric changes among different aetiologies, namely virus-, alcoholism-, non-alcoholic steatohepatitis (NASH)-related differences and different stages of liver cirrhosis.…”

Simple linear measurements of the normal liver: interobserver agreement and correlation with hepatic volume on MRI

“…Estimation of liver size can be used as an index to monitor various aspects of liver disease and response to treatment [1,2] Serial magnetic resonance imaging (MRI) may be used to monitor patient treatment and determine management [3]. Midclavicular (MCL), craniocaudad (CC), or midhepatic (MHP) CC measurements have been used in ultrasound (US) to estimate liver size [4,5].…”

Utility of diffusion-weighted magnetic resonance imaging for liver fibrosis in chronic active hepatitis

“…Thus, conducting liver ADC measurements from the right lobe posterior segment (39) and using multiple b values to prevent perfusional effects from affecting the ADC have been proposed (38). In another study, the authors proposed that the ADC is affected by perfusion rather than diffusion in organs that have a strong blood supply such as the liver (45,46). The negative correlation among the ADC values of RP and LL segments and the absence of a correlation between the RA and LM segments support this view.…”