The basic premise of this article is the importance of extracurricular science activities for students and the self-efficacy that exists in each individual learner. Both can be important factors in achieving learning goals at school. Learning objectives can be achieved effectively if the school provides the best programs and curriculum according to the character development of its students, so teachers must play their role actively, creatively and competently in managing the learning process in the classroom. This research aims to determine the influicer of school-programmed science extracurricular management and self-efficacy to improve scientific literacy skills in middle level students. The focus of the research lies in the level of influicer of science management and self-efficacy in improving scientific literacy skills in Natural Sciences subjects using a quantitative approach to the field research model through interviews, observations and distributing questionnaires to students used as samples. The findings from the research results are (1) There is a significant influence between good science extracurricular management and increased scientific literacy in students, amounting to 0.005 with a confidence value of 5% (2) There is a significant influence between self-efficacy and increased scientific literacy of 0.002 with a confidence value of 5% and (3) The level of effectiveness of these two factors can be seen from the determination valueNagelkerkeamounted to 83.4% and can be said to have a high level of effectiveness, while 16.6% there were other factors that were not included in this research.