Based on the limiting normal cone relative to a set, we present in this paper the novel versions of the limiting coderivative relative to a set and subdifferentials relative to a set of multifunctions and singleton mappings, respectively. In addition to giving the necessary and sufficient conditions for the Aubin property relative to a set of multifunctions, the limiting coderivative relative to a set also provides a coderivative criterion for the metric regularity relative to a set of multifunctions. Besides, our study establishes sudifferential characteristics of the metric regularity and the locally Lipschitz continuity relative to a set for single-valued mappings. In finite dimensional spaces, our results are more general than the previous results. Furthermore, we also give examples to illustrate our results.