Projector with realistic detector scatter modelling for PET list-mode reconstruction

Autret, Awen; Bert, Julien; Strauss, Olivier; Visvikis, Dimitris

doi:10.1109/nssmic.2012.6551759

Cited by 2 publications

(4 citation statements)

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“…An alternative approach based on the use of an Iterative Random IDRF Sampling (IRIS) projector [33] can further improve results. This previously proposed projector has been modified for monolithic crystal based detectors modeling the response associated with a given line of response.…”

Section: Performance Measurements Of the Mindview Scannermentioning

confidence: 99%

The MINDVIEW project: First results

et al. 2018

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We present the first results of the MINDVIEW project. An innovative imaging system for the human brain examination, allowing simultaneous acquisition of PET/MRI images, has been designed and constructed. It consists of a high sensitivity and high resolution PET scanner integrated in a novel, head-dedicated, radio frequency coil for a 3T MRI scanner. Preliminary measurements from the PET scanner show sensitivity 3 times higher than state-of-the-art PET systems that will allow safe repeated studies on the same patient. The achieved spatial resolution, close to 1 mm, will enable differentiation of relevant brain structures for schizophrenia. A cost-effective and simple method of radiopharmaceutical production from C-carbon monoxide and a mini-clean room has been demonstrated. It has been shown thatC-raclopride has higher binding potential in a new VAAT null mutant mouse model of schizophrenia compared to wild type control animals. A significant reduction in TSPO binding has been found in gray matter in a small sample of drug-naïve, first episode psychosis patients, suggesting a reduced number or an altered function of immune cells in brain at early stage schizophrenia.

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Section: Performance Measurements Of the Mindview Scannermentioning

confidence: 99%

The MINDVIEW project: First results

et al. 2018

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“…The third projector considered in this work is the IRIS projector [6]. This projector is based on a multiple-lines approach and is capable of rendering a VOR that naturally varies inside the field-of-view and accurately models the detector geometry and the crystal scatter effects.…”

Section: B Projectorsmentioning

confidence: 99%

“…As proposed in [5], the detector PSF can be modeled with asymmetrical Gaussian functions, although assuming a Gaussian shape may be associated with an approximation. The projector proposed in [6] is based on a complete modeling of the intrinsic detector response function (IDRF) and a multiple-lines approach called iterative random IDRF sampling (IRIS). It allows a complete A.…”

Section: Introductionmentioning

confidence: 99%

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Incorporation of time-of-flight information in PET list-mode reconstruction using a projector with accurate detector PSF modeling

Autret

Bert

Strauss

et al. 2013

2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC)

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In list-mode PET reconstruction the projector is an operator that computes on-the-fly the spatial detector response related to a specific line-of-response (LOR). In the literature, many projectors with PSF modeling have been proposed with different levels of accuracy. A recently proposed projector based on the random sampling of the intrinsic detector response function was shown to accurately model all detector effects including geometry and crystal scatter. Recent PET scanners have the capability to measure the difference in the time arrival of the annihilation gamma photon pairs, also called time-offlight (TOF). Many studies have shown the benefits, in terms of image quality, from the use of the TOF within the reconstruction process. In this study we evaluate the impact of including TOF information within a projector that includes a full modeling of the detector response. A comparative study with non-TOF image reconstruction using a projector with no (Siddon) and a less accurate (Gaussian) detector PSF modeling was also included in this study. All reconstruction algorithms were implemented on multi-GPUs. Results have shown that combining both TOF and PSF allows a double benefit on the reconstructed images. Contrast recovery was improved by nearly a factor of two, and overall execution times including TOF information were reduced by half compared to corresponding non-TOF reconstructions.978-1-4799-0534-8/13/$31.00 ©2013 IEEE

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Projector with realistic detector scatter modelling for PET list-mode reconstruction

Cited by 2 publications

References 9 publications

The MINDVIEW project: First results

The MINDVIEW project: First results

Incorporation of time-of-flight information in PET list-mode reconstruction using a projector with accurate detector PSF modeling

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