Prolactin and Growth Hormone Responses to the Serotonin Antagonist, Metergoline, in Liver Cirrhosis: Further Evidence for Serotoninergic Dysfunction

The Immunology of Prolactin

“…Serum GH levels were also elevated in cirrhotic individuals, which was not influenced by metergoline treatment. 206 Four cases of autoimmune Addison's disease were described in association with hyperprolactinemia. Two females had gallactorrhea.…”

Effects of Naloxone Administration on Pituitary Hormones in Cirrhotic Patients

“…Several abnormalities in pituitary hormone levels both in basal conditions and after various stimuli have been reported in patients with liver cirrhosis (Borzio, Caldara, Ferrari, Barbieri, Borzio and Romussi 1981;Borzio, Caldara, Ferrari, Borzio,Piepoli and Romussi 1982;Salerno, Cocchi, Frigerio, Colombo and Miiller 1980;Van Thiel, Gavaler, Spero, Egler, Wight, Sanghvi, Hasiba and Lewis 1981;Mc Lain, Kromhout, Elson and Van Thiel 1982). These alterations are probably due, at least in part, to a derangement of various neurotransmitters, including dopamine and serotonin, consequent to accumulation of false neurotransmitters (Borzio et al 1981;Salerno et al 1980).…”