Prolapsed hyperplastic gastric polyp causing gastric outlet obstruction, hypergastrinemia, and hematemesis in an infant

Brooks, Glen S.; Frost, E. Scott; Wesselhoeft, Conrad

doi:10.1016/0022-3468(92)90498-v

Cited by 24 publications

(11 citation statements)

References 6 publications

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“…They often bleed, leading to hematemesis, melena or anemia. A prolapsing gastric polyp can also lead to hypergastrinemia with abnormally increased gastric acid production caused by isolation of gastric mucosa from its normal acidic environment [42]. Gastric polyps can be hyperplastic or adenomatous, with a 1.5-3% chance of malignant transformation in hyperplastic polyps, and a higher risk in adenomatous polyps [43].…”

Section: Gastric Polypsmentioning

confidence: 99%

Usual and unusual causes of pediatric gastric outlet obstruction

et al. 2012

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Gastric outlet obstruction in children encompasses a spectrum of disorders that extends beyond hypertrophic pyloric stenosis. Each condition can result in the clinical syndrome of persistent nonbilious vomiting, which can progress to dehydration and electrolyte imbalances. This paper reviews the spectrum of both the common and uncommon entities that cause partial or complete gastric outlet obstruction and their imaging appearances. The correct diagnosis of those with gastric outlet obstruction can be achieved by combining clinical presentation with appropriate imaging, leading to optimal and timely patient management.

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Section: Gastric Polypsmentioning

confidence: 99%

Usual and unusual causes of pediatric gastric outlet obstruction

et al. 2012

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“…Two previous report in non MD has been described in infancy period and required surgical resection secondary to hematemesis and obstructive symptoms[7,8]. Gastric polyps have been described in children receiving long term proton pump inhibitor (PPI) therapy as in our patient[9]; however, the majority of PPI-associated polyps are small (2-8 mm), with a partly translucent surface and usually located in the fundus or proximal in the gastric corpus.…”

Section: Discussionmentioning

confidence: 70%

Management of hyperplastic gastric polyp following upper gastrointestinal bleeding in infant with Menkes’ disease

Belsha

Narula

Urs

et al. 2017

WJGE

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We report a case of an infant with Menkes’ disease (MD) presented at the age of five months, with coffee ground vomiting, melaena with a significant drop of haemoglobin. Urgent endoscopic assessment revealed a friable bleeding trans-pyloric multi-lobulated sessile polyp. Due to further significant upper gastrointestinal bleeding, polypectomy occurred. Endoscopic mucosal resection was performed with a grasp-and-snare technique using a dual channel operating gastroscope. Haemostasis was achieved by application of argon plasma coagulation where required. No perforation occurred. Repeated debridement was required 6 wk after which the growth was excised completely with no further blood transfusion required after that procedure. Histological examination confirmed ulcerated and inflamed hyperplastic polyp. We discuss our endoscopic technique and discuss the reported gastrointestinal manifestation of MD in the literature.

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“…Race was not specified in the majority of cases. Only four pediatric cases have been reported [13,14,16,18] . The pediatric cases presented within the first year of life, mimicked pyloric stenosis, and required surgical removal.…”

Section: Discussionmentioning

confidence: 99%

Intermittent gastric outlet obstruction caused by a prolapsing antral gastric polyp

Parikh

Kelley²,

Rendón³

et al. 2010

WJGO

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Most gastric polyps have an asymptomatic presentation and are an incidental finding on upper endoscopy. Sym ptomatic presentations can range from an ulcerated polyp leading to anemia and occult bleed to complete gastric outlet obstruction. We report a case of an 89year old woman who presented with postprandial nausea and early satiety. Her upper endoscopy revealed a 2 cm pedunculated hyperplastic polyp arising from the antrum of the stomach which was seen prolapsing into the pylorus causing intermittent gastric outlet obstruction. In the present report, we statistically analyzed 39 prolapsing gastric polyps previously reported in the English literature and demonstrate the current utility of monopolar snare polypectomy in establishing a histological diagnosis while offering simultaneous treatment. Additionally, we review the literature for the management of all hyperplastic gastric polyps in relation to advancements in digestive endoscopy.

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Prolapsed hyperplastic gastric polyp causing gastric outlet obstruction, hypergastrinemia, and hematemesis in an infant

Cited by 24 publications

References 6 publications

Usual and unusual causes of pediatric gastric outlet obstruction

Usual and unusual causes of pediatric gastric outlet obstruction

Management of hyperplastic gastric polyp following upper gastrointestinal bleeding in infant with Menkes’ disease

Intermittent gastric outlet obstruction caused by a prolapsing antral gastric polyp

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