Proliferative fasciitis of the chin: A report of the rare case and review of literature

Jyothi, H; Sudha, S; Nair, Resmi G; Remya, K R

doi:10.4103/ijdr.ijdr_8_18

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…Cranial fascitis was differentiated from other types of reactive lesions or tumors that occur in the scalp or skull of infants. (1) Proliferative fasciitis or proliferative myositis in children: 13 Similar to CF, it had rapid growth in a short period and mucinous matrix in histologic morphology, and many large polygonal cells like ganglion cells were scattered in the differential characteristics. Immunohistochemistry showed that spindle cells mainly expressed Vimentin and SMA.…”

Section: Discussionmentioning

confidence: 99%

Infantile Cranial Fasciitis: A Clinicopathologic Evaluation

Cao

Yang

Chen

et al. 2023

Journal of Craniofacial Surgery

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Objective: To investigate the clinicopathologic features, immunophenotype, molecular genetic changes, and differential diagnosis of cranial fasciitis (CF). Methods: The clinical manifestations, imaging, surgical technique, pathologic characteristics, special staining, and immunophenotype, as well as break-apart fluorescence in situ hybridization assay for USP6 of 19 CF cases were analyzed, retrospectively. Results: The patients were 11 boys and 8 girls, aged 5 to 144 months, with a median age of 29 months. There were 5 cases (26.31%) in the temporal bone, 4 cases (21.05%) in the parietal bone, 3 cases (15.78%) in the occipital bone, 3 cases (15.78%) in the frontotemporal bone, 2 cases (10.52%) in the frontal bone, 1 case (5.26%) in the mastoid of middle ear, and 1 case (5.26%) in the external auditory canal. The main clinical manifestations were painless, with the presentation of masses that grew rapidly and frequently eroded the skull. There was no recurrence and no metastasis after the operation. Histologically, the lesion consists of spindle fibroblasts/myofibroblasts arranged in bundles, braided or atypical spokes. Mitotic figures could be seen, but not atypical forms. Immunohistochemical studies showed diffuse strong positive SMA and Vimentin in all CFs. These cells were negative for Calponin, Desmin, β-catenin, S-100, and CD34. The ki-67 proliferation index was 5% to 10%.Ocin blue-PH2.5 staining showed blue-stained mucinous features in the stroma. The positive rate of USP6 gene rearrangement detected by fluorescence in situ hybridization assay was about 10.52%, and the positive rate was not related to age. All patients were observed for 2 to 124 months and showed no signs of recurrence or metastasis. Conclusions: In summary, CF was a benign pseudosarcomatous fasciitis that occurs in the skull of infants. Preoperative diagnosis and differential diagnosis were difficult. Computed tomography typing might be beneficial for imaging diagnosis, and pathologic examination might be the most reliable way to diagnose CF.

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Section: Discussionmentioning

confidence: 99%

Infantile Cranial Fasciitis: A Clinicopathologic Evaluation

Cao

Yang

Chen

et al. 2023

Journal of Craniofacial Surgery

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The first case of proliferative fasciitis of tongue coexistent with squamous cell carcinoma

Nagose

Vaze

Mahajan

et al. 2022

Journal of Oral and Maxillofacial Pathology

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Proliferative fasciitis (PF) is a rare pseudosarcomatous myofibroblastic benign tumor, a subcutaneous counterpart of proliferative myositis. Usually seen in upper extremities, no case has yet been documented in tongue or any other subsites in oral cavity. The present case becomes the first to be reported at this site as well as the first case of synchronous coexistent PF with squamous cell carcinoma (SCC) of tongue. The patient was 50 years male, having a polypoidal swelling at right lateral border of tongue with an ulcer adjacent to it. Histopathologically, the swelling was diagnosed as PF and ulcer as SCC; both the diagnoses were confirmed by immunohistochemistry. The polypoidal lesion was immunopositive for smooth muscle actin and calponin and immunonegative for pan cytokeratin, cytokeratins (5/6), P40 and P63, proving it to be a non-SCC lesion, different from its adjacent ulcerative one.

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Proliferative fasciitis of the chin: A report of the rare case and review of literature

Cited by 2 publications

References 11 publications

Infantile Cranial Fasciitis: A Clinicopathologic Evaluation

Infantile Cranial Fasciitis: A Clinicopathologic Evaluation

The first case of proliferative fasciitis of tongue coexistent with squamous cell carcinoma

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