Prolonged facial edema is an indicator of poor prognosis in patients with head and neck squamous cell carcinoma

Chen, Ming-Huang; Chang, Peter Mu Hsin; Chen, Po Min; Tzeng, Cheng Hwai; Chu, Pen–Yuan; Chang, Shun‐Hsyung; Yang, Muh Hwa

doi:10.1007/s00520-009-0754-8

Cited by 26 publications

(17 citation statements)

References 17 publications

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“…[24] reported a retrospective chart review of 264 patients with squamous cell carcinoma of the head and neck. Thirty-two patients (12.1%) were identified with facial edema lasting more than 100 days.…”

Section: Review Of Current Literaturementioning

confidence: 99%

Editorial introductions

Smith

Lewin²

2010

Current Opinion in Otolaryngology &Amp; Head &Amp; Neck Surgery

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Purpose of review Head and neck lymphedema (HNL) is a common and often debilitating cancer treatment effect that is under-researched and ill defined. We examined current literature and reviewed historical treatment approaches. We propose a model for evaluation and treatment of HNL used at The University of Texas M. D. Anderson Cancer Center (MDACC) for patients with head and neck cancer (HNC). Recent findings Despite the morbidity associated with HNL in patients with HNC, to our knowledge, no article has been published within the past 18 months whose primary focus is HNL. Eight publications included HNL but only as a secondary focus related to treatment effect, risk of dysphagia, prognostic indicator of underlying disease, and quality of life. A potential benefit of Selenium treatment to reduce HNL was reported. Summary This article highlights the recent literature regarding HNL in patients treated for HNC. Although HNL is reported as a potential complication of HNC treatment, no clear definition of the disease or its management are published. Our early experience using an objective evaluation and treatment protocol holds promise for a better understanding of HNL in patients treated for head and neck malignancy.

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Section: Review Of Current Literaturementioning

confidence: 99%

Editorial introductions

Smith

Lewin²

2010

Current Opinion in Otolaryngology &Amp; Head &Amp; Neck Surgery

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“…The late diagnosis of these neoplasms is related to a worse prognosis, raising the likelihood of sequelae and deformities. When a head and neck cancer diagnosis is delayed, the expected outcome is worse, with more invasive and mutilating therapeutic interventions that affect the lymphatic system and increase the risk of lymphedema (18,22).…”

Section: General Aspects Of Head and Neck Lymphedemamentioning

confidence: 99%

“…The overall prevalence of lymphedema among head and neck cancer patients ranges from 12% and 75% (9,14,22). This discrepancy may be explained by a lack of a standard diagnosis and universal assessment criteria, as well as differences among the therapeutic procedures used to treat this type of cancer (7,9,22).…”

Section: General Aspects Of Head and Neck Lymphedemamentioning

confidence: 99%

“…Assessment is essential for the effective treatment of lymphedema, however, most studies addressing the topic report that the instruments used to measure head and neck cancer-related lymphedema are insuf icient because the procedures used to treat this type of cancer are mutilating and involve the resection of lymph nodes and other structures, reducing tissue volume in the compromised area, hindering the effective use of circumferential techniques or veri ication of the distance between two landmarks (7,9,18,22,24,25).…”

Section: Instruments and Techniques Used To Assess Head And Neck Lympmentioning

confidence: 99%

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Head and neck lymphedema: what is the physical therapy approach? A literature review

Justina

Dias

2016

Fisioter. mov.

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Introduction: Head and neck lymphedema is considered a chronic and complex complication with potential to cause physical, functional, emotional and social impairment. Objective: To identify the approaches to physical therapy used to treat head and neck cancer-related lymphedema. Method: A bibliographic search was conducted in February and March 2012 in books and electronic databases, LILACS, MEDLINE, SCIELO, Cochrane, PEDro, and BDTD using the following keywords: lymphedema, treatment, head and neck cancer, and physical therapy connected by the Boolean operator AND without a speci ic time frame. Results and discussion: Early diagnosis and assessment is key to properly managing and effectively treating lymphedema. Diagnosis is reached through clinical history and physical assessment by measuring the distance between two anatomical landmarks, circumference measures, and lymphedema rating scales. Complex decongestive therapy, which includes manual lymph drainage, compressive bandaging, kinesiotherapy and skin care, is the technique most frequently used and currently considered to be the gold standard. Conclusions: No consensus is reported in the literature in regard to a standard procedure to assess and treat head and neck cancer-related lymphedema. Assessments and treatments described in the literature are mainly restricted to the limbs; therefore, further studies are needed to support effective clinical actions in the physical therapy approach to this condition.Keywords: Lymphedema. Head and neck neoplasms. Physical therapy modalities. Therapeutics.

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“…Some pretreatment factors had been reported to predict poor prognosis, such as co-morbidity index determined by the Adult Comorbidity Evaluation-27 (ACE-27) score, 3 hypercalcemia, 4e7 pre-treatment hematologic profile, or prolonged facial edema. 8,9 Other factors have also been shown to be associated with a poor prognosis in various kinds of cancer other than HNSCC, such as tumor-related leukocytosis, 10 pretreatment anemia, 11e15 pretreatment thrombocytosis, 16e23 levels of pretreatment serum albumin 24,25 and serum lactate dehydrogenase (LDH), 26e28 and hypercalcemia. 29 Some molecular prognostic factors, such as, human papilloma virus 16 (HPV-16), 30e33 vascular endothelial growth factor (VEGF), 31 and epidermal growth factor receptor (EGFR) 31,33 were also recently reported to influence the prognosis of HNSCC.…”

Section: Introductionmentioning

confidence: 99%

Pretreatment risk stratification for non-metastatic head and neck squamous cell carcinoma in a high-prevalence area

Hsieh

Chang

Chen

et al. 2011

Journal of the Chinese Medical Association

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Prolonged facial edema is an indicator of poor prognosis in patients with head and neck squamous cell carcinoma

Abstract: Prolonged facial edema may reflect the underlying disease status, and it can be applied as a prognostic marker in patients with HNSCC.

Cited by 26 publications

References 17 publications

Editorial introductions

Editorial introductions

Head and neck lymphedema: what is the physical therapy approach? A literature review

Pretreatment risk stratification for non-metastatic head and neck squamous cell carcinoma in a high-prevalence area

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