2018
DOI: 10.1101/319491
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Prolyl Endopeptidase (PREP) is Involved in the Reproductive Functions and Cytoskeletal Organization in Rat Spermatogenesis and in Mammalian Sperm

Abstract: In this paper we show the co-localization of the enzyme PREP with tubulin during the first wave of rat spermatogenesis and in mature gametes of rat and human. 2 AbstractProlyl endopeptidase (PREP) is an enzyme which cleaves several peptide hormones and 1 neuropeptides at the carboxyl side of proline residues, involved in many biological processes, 2 including cell proliferation and differentiation, glucose metabolism, learning, memory and cognitive 3 disorders. Moreover, PREP was identified as binding partner … Show more

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