Prominent papillary dermal edema in dermatophytosis (tinea corporis)<sup>*</sup>

Hoss, Diane M.; Berke, Adrienne; Kerr, Philip; Grant‐Kels, Jane M.; Murphy, Michael J.

doi:10.1111/j.1600-0560.2009.01314.x

Cited by 12 publications

(16 citation statements)

References 12 publications

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“…Papillary dermal edema was observed in three patients. This feature has also been noted by other authors …”

Section: Discussionsupporting

confidence: 90%

“…Al‐Amiri et al showed that only 45% of studied cases were correctly diagnosed as tinea clinically. Hoss et al published similar findings, with only 44% of cases showing concordance between clinical suspicion and a histopathologic diagnosis of tinea. Along those lines, our study have showed that only 57.28% of included cases where correctly suspected tinea lesions.…”

Section: Discussionmentioning

confidence: 78%

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When to suspect tinea; a histopathologic study of 103 cases of PAS‐positive tinea

et al. 2016

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“…Papillary dermal edema was observed in three patients. This feature has also been noted by other authors …”

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 78%

When to suspect tinea; a histopathologic study of 103 cases of PAS‐positive tinea

et al. 2016

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“…However, coexistence of parakeratosis and neutrophils can make visualization of hyphae and spores almost impossible, so PAS staining procedure is warranted. confirmed by Hoss et al, was present in a series of 16 reported cases of dermatophytic infections in glabrous skin (13).…”

Section: Psoriasiform Reaction Patternsupporting

confidence: 67%

The role of histopathology in the diagnosis of dermatophytoses / Značaj patohistološkog nalaza u dijagnostici dermatofitoza

Gocev¹,

Damevska²

2010

Serbian Journal of Dermatology and Venerology

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Histopathological analysis is not a routine procedure for diagnosing fungal skin infections. In the histopathological specimens, fungi are visible only when using special stain such as periodic acid-Schiff (PAS). However, histopathological analysis may not be performed in small laboratories. Histopathological characteristics of fungal skin infections are not specific. In all skin biopsy cases, obtained without clinical suspicion of fungal infection, the knowledge of certain, most frequent histopathological reaction patterns, as well as specific histopathological indicators (a diagnostic histopathological "clue"), of certain superficial mycoses e.g., dermatophytoses, may raise a suspicion of fungal infection and warrant a fungal-specific staining. A retrospective analysis of all PAS-stained sections was carried out. All PAS-positive biopsy specimens were assessed for clinical features, histopathological patterns of skin reactions, and presence of histopathological indicators. Our results have shown that out of the total of 361 PAS-stained sections, fungal hyphae were identified in 12 (3.3%) specimens. In 5 (1.4%) cases, the diagnosis of fungal infection was suspected on clinical grounds, while in 7 (1.9%) cases detection of fungi was an unexpected finding. The most frequent type of histopathological pattern was spongiotic, and the most frequent histopathological indicator was the presence of neutrophils within the epidermis. Our results confirm that dermatophytoses may present with clinical and histological non-specific findings. PAS staining represents a relatively cheap and simple fungal-specific staining. It has been suggested that it not only confirms that the selected material is actually invaded, but also reduces the number of false-negative direct reports, where fungi are cultured from a microscopically negative specimen. Apart from a small percentage of positive findings, our results justify the need for routine PAS staining of all clinically and histologically non-specific inflammatory skin conditions.

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“…In acute lesions the epidermis shows spongiosis and neutrophilic microabscesses. Lastly, the dermis shows various degrees of perivascular lymphocytes and plasma cells, and in some cases there may be prominent papillary dermal edema (71). When a dermatophyte causes severe inflammation of hair follicles and shafts, it is called kerion if the infiltrate is primarily neutrophilic or Majocchi's granuloma if chronic with prominent mononuclear inflammation.…”

Section: Mucormycosis (Zygomycosis) (I) Epidemiologicmentioning

confidence: 99%

Histopathologic Diagnosis of Fungal Infections in the 21st Century

2011

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SUMMARY Fungal infections are becoming more frequent because of expansion of at-risk populations and the use of treatment modalities that permit longer survival of these patients. Because histopathologic examination of tissues detects fungal invasion of tissues and vessels as well as the host reaction to the fungus, it is and will remain an important tool to define the diagnostic significance of positive culture isolates or results from PCR testing. However, there are very few instances where the morphological characteristics of fungi are specific. Therefore, histopathologic diagnosis should be primarily descriptive of the fungus and should include the presence or absence of tissue invasion and the host reaction to the infection. The pathology report should also include a comment stating the most frequent fungi associated with that morphology as well as other possible fungi and parasites that should be considered in the differential diagnosis. Alternate techniques have been used to determine the specific agent present in the histopathologic specimen, including immunohistochemistry, in situ hybridization, and PCR. In addition, techniques such as laser microdissection will be useful to detect the now more frequently recognized dual fungal infections and the local environment in which this phenomenon occurs.

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Prominent papillary dermal edema in dermatophytosis (tinea corporis)^*

Cited by 12 publications

References 12 publications

When to suspect tinea; a histopathologic study of 103 cases of PAS‐positive tinea

When to suspect tinea; a histopathologic study of 103 cases of PAS‐positive tinea

The role of histopathology in the diagnosis of dermatophytoses / Značaj patohistološkog nalaza u dijagnostici dermatofitoza

Histopathologic Diagnosis of Fungal Infections in the 21st Century

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Prominent papillary dermal edema in dermatophytosis (tinea corporis)*

Cited by 12 publications

References 12 publications

When to suspect tinea; a histopathologic study of 103 cases of PAS‐positive tinea

When to suspect tinea; a histopathologic study of 103 cases of PAS‐positive tinea

The role of histopathology in the diagnosis of dermatophytoses / Značaj patohistološkog nalaza u dijagnostici dermatofitoza

Histopathologic Diagnosis of Fungal Infections in the 21st Century

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Prominent papillary dermal edema in dermatophytosis (tinea corporis)^*