Promising microRNAs in pre-diagnostic serum associated with lung cancer up to eight years before diagnosis: a HUNT study
Ioannis Fotopoulos,
Olav Toai Duc Nguyen,
Therese Haugdahl Nøst
et al.
Abstract:Introduction
Blood biomarkers for early detection of lung cancer (LC) are in demand. There are few studies of the full microRNome in serum of asymptomatic subjects that later develop LC. Here we searched for novel microRNA biomarkers in blood from non-cancer, ever-smokers populations up to eight years before diagnosis.
Methods
Serum samples from 98,737 subjects from two prospective population studies, HUNT2 and HUNT3, were considered initially. Inc… Show more
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