2023
DOI: 10.3390/jcm12185878
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Promising Novel Therapies in the Treatment of Aortic and Visceral Aneurysms

Theodora M. Stougiannou,
Konstantinos C. Christodoulou,
Efstratios Georgakarakos
et al.

Abstract: Aortic and visceral aneurysms affect large arterial vessels, including the thoracic and abdominal aorta, as well as visceral arterial branches, such as the splenic, hepatic, and mesenteric arteries, respectively. Although these clinical entities have not been equally researched, it seems that they might share certain common pathophysiological changes and molecular mechanisms. The yet limited published data, with regard to newly designed, novel therapies, could serve as a nidus for the evaluation and potential … Show more

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Cited by 2 publications
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“…miRNAs have been reported to be critical regulators of cardiovascular function ( Abubakar et al, 2023 ). Nevertheless, their role as biomarkers for the diagnosis of these diseases, including ATAA, and as therapeutic targets remains to be defined ( Stougiannou, et al, 2023 ). Therefore, understanding and further investigating the role of miRNA in cardiovascular diseases may allow us to identify new potential prognostic factors and develop more specific therapeutic strategies for ATAA.…”
Section: Epigenetic Mechanisms: Non-coding Rna_mirnamentioning
confidence: 99%
“…miRNAs have been reported to be critical regulators of cardiovascular function ( Abubakar et al, 2023 ). Nevertheless, their role as biomarkers for the diagnosis of these diseases, including ATAA, and as therapeutic targets remains to be defined ( Stougiannou, et al, 2023 ). Therefore, understanding and further investigating the role of miRNA in cardiovascular diseases may allow us to identify new potential prognostic factors and develop more specific therapeutic strategies for ATAA.…”
Section: Epigenetic Mechanisms: Non-coding Rna_mirnamentioning
confidence: 99%