Promoter regions of sxtA and sxtG reveal relationship between saxitoxin biosynthesis and photosynthesis in toxic Alexandrium catenella

Environmental Factors Modulate Saxitoxins (STXs) Production in Toxic Dinoflagellate Alexandrium: An Updated Review of STXs and Synthesis Gene Aspects

“…In summary, the expression patterns of sxtA and sxtG and their correlation with PST production were different under salinity and water temperature conditions. Further genetic studies were also conducted focusing on the secondary core sxtG gene, which catalyzes the incorporation of the amidino group from the product of sxtA in the STX synthesis process [141,143]. Similar to sxtA, the loss and/or modification of the gene results in the breakdown of the initial reaction in STX production, and it may lead to a loss of the ability of toxin production in both cyanobacteria and dinoflagellates [144].…”