In the standard lattice domain-wall fermion formulation, one needs two flat domain-walls where both of the left- and right-handed massless modes appear. In this work we investigate a single domain-wall system with a nontrivial curved background. Specifically we consider a massive fermion on a three-dimensional square lattice, whose domain-wall is a two-dimensional sphere. In the free theory, we find that a single Weyl fermion is localized at the wall and it feels gravity through the induced spin connection. With a topologically nontrivial U(1) link gauge field, however, we find a zero mode with the opposite chirality localized at the center where the gauge field is singular. In the latter case, the low-energy effective theory is not chiral but vectorlike. We discuss how to circumvent this obstacle in formulating lattice chiral gauge theory in the single domain-wall fermion system.