Properties of an acrylic resin after immersion in antiseptic soaps: Low-cost, easy-access procedure for the prevention of denture stomatitis

Abstract

Denture stomatitis triggered by Candida species requires better preventive measures. This study evaluated the physical and biological properties of a denture base acrylic resin after immersion in antiseptic soaps. Acrylic resin specimens were prepared and stored in distinct solutions for 0, 7, 14, 21, and 28 days. The solutions were as follows: DW: distilled water at 37°C (control group); DS: cycles of daily immersion in Dettol soap for 8 hours at room temperature, followed by immersion in distilled water for 16 hours at 37°C; PS: cycles of daily immersion in Protex soap, as described for the previous group; LS: cycles of daily immersion in Lifebuoy soap, as described for the DS group. The parameters evaluated at each time point were the following: biofilm formation capacity by Candida albicans and reduction of preformed fungal biofilms, cytotoxicity, surface roughness, hardness, and color change. For the fungal adhesion phase, the type of soap had a statistically significant effect (p = 0.0292), but after 24 hours, no differences were found between solutions or between storage times. Regarding the efficacy of biofilm reduction, there was a significant difference when the groups were compared to each other (p = 0.014). Dettol and Lifebuoy eliminated the preformed biofilm on the specimens. Moreover, all the soaps were classified as non-cytotoxic (on HaCaT cell line) because there was no difference in cell viability between the different groups, except after 21 days, when a decrease in cell viability occurred, regardless of the type of soap. Regarding the roughness, there was no statistically significant difference (p > 0.05) between the groups. Lifebuoy decreased resin hardness regardless of storage time (p = 0.003). After 21 and 28 days of storage, there was an increase in hardness value, regardless of the type of soap. The specimens’ color, according to the National Bureau of Standards values, ranged from 0.27 to 0.58 (i.e., imperceptible or mild color changes). In general, the disinfectant soaps were not able to prevent biofilm formation, but all the soaps were effective in reducing the preformed biofilm. In addition, all soaps were non-cytotoxic and did not change surface roughness, hardness (except Lifebuoy), and color (except Lifebuoy). Therefore, immersion in two antiseptic soaps (Protex and Dettol) may be a cheap and easy procedure for preventing denture stomatitis.

The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka

“…These MIC values are lower than those reported for most of the ubiquitous phyto-constituents in the literature [40,41]. Moreover, the disinfectant potency of the G. cambogia extracts was comparable to that of the commercial disinfectant Lifebuoy ® soap used as reference [23]. Although the disinfectant capacity of an obicure tea extract containing green tea, G. cambogia, ginger and pepirene was determined from zone of inhibition as well as by totally incubating in a broth and visualizing the presence or absence of turbidity [42], to the best of our knowledge, this is the first report on the evaluation of disinfectant potency of G. cambogia extract on different surfaces that might correlate to smooth and rough surfaces in hospital settings.…”

“…The disinfectant activity was assessed after treating smooth and rough surfaces with different plant extracts; the disinfectant Lifebuoy ® soap (containing silver as active ingredient [23]) was used as the reference. As shown in Table 4, a prominent disinfectant efficiency was observed especially with the n-hexane extract of G. cambogia against all the tested microorganisms on both types of surfaces.…”

(Lack of) oral hygiene care for hospitalized elderly patients

“…An alternative of providing cost control in prosthesis hygiene assistance was pointed out in a study with the use of antiseptic soaps. In the study that aimed to assess the physical and biological properties of an acrylic resin, based on prostheses, after immersion in antiseptic soaps, it was successful in controlling Candida albicans, which can be a cheap and easy procedure to prevent stomatitis by dental prosthesis (27) .…”

Assessment of surface roughness changes on orthodontic acrylic resin by all-in-one spray disinfectant solutions

“…13 Several studies reported some changes related to the strength, hardness, color, and roughness of the acrylic resin materials following disinfection. 9,11,38 Another recent study found that the short-term acrylic resin disinfection did not affect the flexural strength, surface roughness, and the color of different commercially available orthodontic acrylic resins. 33 These uncertain outcomes could be related to the type of the material, the type of disinfectant, the followed protocol, and disinfection duration.…”

“…Solutions applied for intended disinfection should preserve their physical and mechanical properties, not compromising the surface integrity of the material. 9 The extent of the roughness of an orthodontic appliance can influence the biofilm attachment, which might accelerate the colonization of microorganisms and alter the appliance’s color. 10 This condition is critical as orthodontic appliances must have a smooth surface to prevent the adhesion and colonization of oral microbes.…”