Properties of high-purity iron

Sarrak, V. I.; Shiryaev, V. I.; Éntin, R. I.

doi:10.1007/bf00652049

Cited by 10 publications

(1 citation statement)

References 2 publications

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“…Moreover, significant difference in the elastic behavior of Fe and VH contributes to crack development. Young’s modulus of pure Fe ranges between 187 and 214 GPa [42]. While that of VH has not been reported, it can be roughly estimated from the values of different organic pharmaceutical excipients such as starch and microcrystalline cellulose that are <10 GPa [43–45].…”

Section: Resultsmentioning

confidence: 99%

Drug-eluting biodegradable metals and metal-ceramic composites: High strength and delayed drug release

Sharipova

Бакина

Ложкомоев

et al. 2022

Preprint

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Biodegradable metals emerged as promising temporary bone implants. The integration of additional features such as local drug delivery (LDD) can also support their osteointegration, promote bone regeneration, and prevent biomaterial-centered infections that are difficult to treat. LDD is achieved by drug-eluting coatings or porous implants where the drug is impregnated after implant fabrication because the high temperatures used during conventional production processes would result in their thermal decomposition. We produced biodegradable iron (Fe)-based vancomycin (VH)-eluting metals and metal-ceramic composites by a simple high-pressure consolidation/cold sintering (CS) process at room temperature that display high mechanical strength and antibacterial activity. Aiming to expand the application of this production method and shed light into the drug loading and release mechanisms in this type of biomaterials, this work reports on the production and characterization of VH-loaded Fe and Fe-iron oxide (Fe2O3) composites (Fe-Fe2O3). We use focus ion beam milling for the first time to investigate the drug-metal interface and investigate the mechanical and degradation properties of VH-free and VH-loaded Fe and Fe-Fe2O3. Results show very high mechanical strength of drug-eluting Fe and Fe-Fe2O3 composites (up to than 780 MPa under compression, exceeding the maximum strength of cancellous bone more than three times) accompanied by a delayed drug release. Then, we confirm the good antimicrobial activity against Staphylococcus aureus and cell compatibility with the murine embryonic fibroblast cell line NIH/3T3 in vitro. Overall results confirm the promise of drug-eluting metals and metal-ceramic composites for LDD in bone.

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Section: Resultsmentioning

confidence: 99%

Drug-eluting biodegradable metals and metal-ceramic composites: High strength and delayed drug release

Sharipova

Бакина

Ложкомоев

et al. 2022

Preprint

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Understanding the Effects of Manufacturing Attributes on Damage Tolerance of Additively Manufactured Parts and Exploring Synergy Among Process‐Structure‐Properties. A Comprehensive Review

Uddin,

Butt,

Kvvssn

et al. 2024

Engineering Reports

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Additive Manufacturing (AM) has revolutionized the production industry by offering design freedom with shorter lead times and reduced material wastage. However, the damage tolerance (DT) of AM parts is a significant concern due to their microstructural and geometric complexities, which affect their mechanical performance. This article aims to provide a comprehensive overview of the manufacturing parameters affecting the components produced by AM specifically selective laser melting (SLM). Detailed discussions are presented on the effects of manufacturing attributes on the microstructure, defects, and mechanical characteristics of AM parts. Depending on these aspects, basic concepts are studied and critically explained specifically for AM materials. The basic criterion for damage‐tolerant component design, the criterion for fatigue and fracture properties, and the effect of the defects on fatigue life are critically presented. In addition, the effect of different types of gradation on the crack growth behavior of samples processed by SLM is also investigated in depth. There is currently a lack of a specific review study in the literature that establishes a connection between process attributes and metallographic properties, and their impact on the damage behavior of additively manufactured parts. This gap in research highlights the need for a comprehensive review to bridge this knowledge deficit and provide valuable insights for understanding the relationships between manufacturing processes, material characteristics, and the structural integrity of additively manufactured components. This review concludes by addressing the challenges and opportunities in designing and qualifying AM parts for damage tolerance.

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