The paper evaluates the feasibility of reducing clinker in the Portland Cement production using local metakaolin in Burkina Faso. Standardized testing methods have been used for this purpose, and experiments were performed on mortar prisms containing different amounts of metakaolin. Important results about the physical, mechanical and durability characterization of blended mortars were carried out in this study. The obtained results are discussed based on available literature data. These results have shown increased physical and durability properties for blended mortars. Although the mechanical strengths remained relatively low for higher MK incorporations, the latter grow to surpass these of PC mortars (the reference) at 28, 56 and 90 days of curing. The results in the paper, have confirmed the possibility of using metakaolin to partially substitute cement, a possibility to reduce the CO2 production by the cement industry in Burkina Faso.