The objective of this work was to evaluate the performance of three natural fibers, namely, bagasse, kenaf bast fibers and cotton stalk, to produce particleboard suitable for application in green furniture and thermal insulation, using tannins and casein as natural matrices at the concentration of 15%. The particleboards were tested according to the relevant European standards to determine their mechanical properties, physical properties and thermal conductivity. The results showed that particleboards made from bagasse fibers and cotton stalks with casein adhesives exhibited higher mechanical performance and complied with European standards for board used for furniture and interior fitments. The particleboards prepared using tannins failed to satisfy the EN standards. All particleboards met the thermal conductivity requirements of the European standards.