Properties of Photoresist Polymers

Lin, Qinghuang

doi:10.1007/978-0-387-69002-5_57

Cited by 15 publications

(10 citation statements)

References 18 publications

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“…Conversely, negative photoresists are hardened by UV-light exposure, and thus a solvent will wash away the unexposed areas, resulting in an inverse pattern of the mask (a negative of the desired microfluidic design). Although negative photoresists are more prone to pattern distortions than their positive counterparts, they have better adhesion to different materials and lower manufacturing costs, making them a better choice when the process does not require very high resolution 35 . Depending on the desired purpose, thickness and adhesion, several manufacturers offer a wide range of positive and negative photoresists.…”

Section: Experimental Designmentioning

confidence: 99%

A microfluidics-based method for measuring neuronal activity in Drosophila chemosensory neurons

et al. 2016

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Animals possess highly specialized sensory neurons that are capable of perceiving information about a continuously changing environment. Measuring neuronal activity in these cells is an important step toward understanding the basic coding principles, as well as the spatial and temporal dynamics, of sensory systems. The fruit fly Drosophila melanogaster is widely used as a genetic model organism to uncover basic mechanisms of taste coding and odor perception [1][2][3][4][5][6][7] . Recent insights into the molecular and functional mechanisms of sensory perception in Drosophila have been achieved by the use of single-sensillum recordings of adult taste or olfactory sensilla 1,4,[8][9][10][11][12][13] . This method enables sensitive measurements of action potential patterns and shows whether responses are excitatory or inhibitory, but drawing final conclusions about the individual firing neuron is difficult, as each sensillum contains two to four neurons 14 . In the larva, multicellular electrophysiological measurements of the taste system have been performed, but this method is technically challenging and it is not clear how many taste neurons are housed in which sensillum 15 .Microfluidic devices have been used previously to image command interneurons (AVA) and sensory neurons (ASH) in the nematode Caenorhabditis elegans and for studies of axotomy in peripheral sensory neurons of Drosophila larvae [16][17][18] . To implement a similar strategy for Drosophila larval chemosensation, we developed a simple and widely applicable microfluidic chip. We used this custom-made microfluidic device to deliver precise and temporally restricted tastant stimulation in the first published physiological characterization of individual larval gustatory receptor neurons (GRNs) expressing the calcium sensor GCaMP5 (ref. 19). Development of the protocolThe design of the chip is simple. It contains a single channel that is connected to a chamber in which the sample can be mounted to bring it into contact with fluids in the channel. The chamber was originally designed to exactly fit the head of a third-instar Drosophila larva; however, it is also suitable for the proboscis or the leg of an adult fly. The channel for delivering stimulants is relatively broad, designed at a width of 1 mm to reduce flow pressure on the sample. We use a single-channel system in which changes of liquids are performed by the tubing system outside the chip, allowing a relatively slow flow rate inside the chip. Here we provide information required for the design and production of this microfluidic device ( Fig. 1; Supplementary Data), as well as a detailed protocol for live imaging to acquire GCaMP-based calcium imaging (Figs. 2 and 3). By introducing the larval head, or the adult proboscis or leg, into the chamber, neuronal activity can be recorded while chemosensory neurons are in contact with the solution pumped through the channel (Figs. 2 and 3).Overview of the procedure An overview of the workflow involved in implementing the procedure is provided in Figu...

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Section: Experimental Designmentioning

confidence: 99%

A microfluidics-based method for measuring neuronal activity in Drosophila chemosensory neurons

et al. 2016

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“…In addition to detecting inflammatory and disease foci, photosensitive compounds are also used in anti-cancer therapy (so-called photodynamic therapy, PDT). Photosensitive compounds are also widely applied in modern technologies, e.g., as photoresists for optical lithography [ 6 , 7 ], sensitizers for solar cells [ 8 ], or initiators in fast photopolymerization processes [ 9 ], and recently also in light-controlled radical polymerization [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes

et al. 2021

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Chitosan is a valuable, functional, and biodegradable polysaccharide that can be modified to expand its applications. This work aimed to obtain chitosan derivatives with fluorescent properties. Three heterocyclic aromatic dyes (based on benzimidazole, benzoxazole, and benzothiazole) were synthesized and used for the chemical modification of chitosan. Emission spectroscopy revealed the strong fluorescent properties of the obtained chitosan derivatives even at a low N-substitution degree of the dye. The effect of high-energy ultraviolet radiation (UV–C) on modified chitosan samples was studied in solution with UV–Vis spectroscopy and in the solid state with FTIR spectroscopy. Moreover, cytotoxicity towards three different cell types was evaluated to estimate the possibilities of biomedical applications of such fluorescent chitosan-based materials. It was found that the three new derivatives of chitosan were characterized by good resistance to UV–C, which suggests the possibility of using these materials in medicine and various industrial sectors.

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“…Photolithography [ 4 ] is most commonly used in the microelectronics industry. The topology obtained with this technology is formed due to a photomask [ 5 ], a replica of which is created on the surface of a substrate by illuminating the photoresist [ 6 ] deposited on the surface through this photomask. After the photoresist has been developed, it is possible to etch the substrate or apply layers to obtain the desired topology.…”

Section: Introductionmentioning

confidence: 99%

Features of Fabrication of Titanium Dioxide Based Coatings for Non-Lithographic Template Electrochemical Synthesis of Micron Metal Particle Arrays

Arbenin

Zemtsova

Orekhov

et al. 2021

Gels

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This work is devoted to the development of non-lithographic template methods of synthesis. These methods have a significant advantage in terms of structure formation: there is no need to design and produce masks, which greatly simplifies the process, and more of them can work with nonplanar substrates. The purpose of this study was to reveal the conditions for the synthesis of titanium dioxide xerogel films of different topologies as well as to develop a technique for non-lithographic template electrochemical synthesis of micron metal particles arrays and to study the structure of the resulting coatings. The films were deposited on the surface of substrates via dip coating. Specific topology of the films was achieved by template sol-gel synthesis. Their structures were analyzed by SEM and XRD. Template synthesis of metal micro particles were realized by pulsed electrochemical deposition of metals into the perforations of xerogel films. Obtained materials were analyzed by SEM and XRD; the element distribution on the surface was determined by the EDS detector of SEM. Based on the analysis results, we suggest the mechanisms of formation of the xerogel topology and proved the efficiency of pulsed electrodeposition for template synthesis of micron particles arrays.

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Properties of Photoresist Polymers

Cited by 15 publications

References 18 publications

A microfluidics-based method for measuring neuronal activity in Drosophila chemosensory neurons

A microfluidics-based method for measuring neuronal activity in Drosophila chemosensory neurons

Fluorescent Chitosan Modified with Heterocyclic Aromatic Dyes

Features of Fabrication of Titanium Dioxide Based Coatings for Non-Lithographic Template Electrochemical Synthesis of Micron Metal Particle Arrays

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