Property Investigation of Replaceable PDMS Membrane as an Actuator in Microfluidic Device

Yuan, Yapeng; Yalikun, Yaxiaer; Ota, Noriyasu; Tanaka, Yo

doi:10.3390/act7040068

Cited by 9 publications

(6 citation statements)

References 55 publications

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“…They comprise micron-sized magnetically soft/hard particles integrated into an elastomer matrix. MAEs are used in several engineering applications because of their exceptional macroscopic shape response to an applied magnetic field and a magneto-mechanical coupled behavior [1][2][3][4][5][6][7]. General applications of MAEs include actuators, sensors, adaptively tuned vibration absorbers, dampers, microfluid transport systems, adaptive engine mounts [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Field-Induced Transversely Isotropic Shear Response of Ellipsoidal Magnetoactive Elastomers

2021

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Magnetoactive elastomers (MAEs) claim a vital place in the class of field-controllable materials due to their tunable stiffness and the ability to change their macroscopic shape in the presence of an external magnetic field. In the present work, three principal geometries of shear deformation were investigated with respect to the applied magnetic field. The physical model that considers dipole-dipole interactions between magnetized particles was used to study the stress-strain behavior of ellipsoidal MAEs. The magneto-rheological effect for different shapes of the MAE sample ranging from disc-like (highly oblate) to rod-like (highly prolate) samples was investigated along and transverse to the field direction. The rotation of the MAE during the shear deformation leads to a non-symmetric Cauchy stress tensor due to a field-induced magnetic torque. We show that the external magnetic field induces a mechanical anisotropy along the field direction by determining the distinct magneto-mechanical behavior of MAEs with respect to the orientation of the magnetic field to shear deformation.

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Section: Introductionmentioning

confidence: 99%

Field-Induced Transversely Isotropic Shear Response of Ellipsoidal Magnetoactive Elastomers

2021

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“…The liquid pre‐polymer base and the cross‐linking agent were mixed at a ratio of 10:1 by weight. Then, mixed PDMS was poured over the master to create a layer of 2–10 mm thickness and the coated master was heated at 80°C in an oven for 1 h. The cured PDMS was then carefully peeled off the master and trimmed to the suitable size . This PDMS layer and a glass slide (70 × 30 mm, 0.7‐mm thickness) were then exposed to oxygen plasma (10 W, 10 s) in a plasma generator (FA‐1; SAMCO, Tokyo, Japan) to form the PDMS microfluidic device by bonding the plasma‐treated layers.…”

Section: Methodsmentioning

confidence: 99%

“…In simulations, PDMS was assumed to be a linear elastic material with the density (ρ),Young's modulus (E), and Poisson ratio (ν) of 970 kg/m 3 , 750 KPa , and 0.5, respectively. Glass was assumed to be a linear elastic material with the density, Young's modulus, and Poisson ratio of 2,500 kg/m 3 , 80 GPa, and 0.25, respectively.…”

Section: Methodsmentioning

confidence: 99%

Effects of Flow‐Induced Microfluidic Chip Wall Deformation on Imaging Flow Cytometry

et al. 2019

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Imaging flow cytometry is a powerful tool by virtue of its capability for high‐throughput cell analysis. The advent of high‐speed optical imaging methods on a microfluidic platform has significantly improved cell throughput and brought many degrees of freedom to instrumentation and applications over the last decade, but it also poses a predicament on microfluidic chips. Specifically, as the throughput increases, the flow speed also increases (currently reaching 10 m/s): consequently, the increased hydrodynamic pressure on the microfluidic chip deforms the wall of the microchannel and produces detrimental effects lead to defocused and blur image. Here, we present a comprehensive study of the effects of flow‐induced microfluidic chip wall deformation on imaging flow cytometry. We fabricated three types of microfluidic chips with the same geometry and different degrees of stiffness made of polydimethylsiloxane (PDMS) and glass to investigate material influence on image quality. First, we found the maximum deformation of a PDMS microchannel was >60 μm at a pressure of 0.6 MPa, while no appreciable deformation was identified in a glass microchannel at the same pressure. Second, we found the deviation of lag time that indicating velocity difference of migrating microbeads due to the deformation of the microchannel was 29.3 ms in a PDMS microchannel and 14.9 ms in a glass microchannel. Third, the glass microchannel focused cells into a slightly narrower stream in the X‐Y plane and a significantly narrower stream in the Z‐axis direction (focusing percentages were increased 30%, 32%, and 5.7% in the glass channel at flow velocities of 0.5, 1.5, and 3 m/s, respectively), and the glass microchannel showed stabler equilibrium positions of focused cells regardless of flow velocity. Finally, we achieved the world's fastest imaging flow cytometry by combining a glass microfluidic device with an optofluidic time‐stretch microscopy imaging technique at a flow velocity of 25 m/s. © 2019 International Society for Advancement of Cytometry

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“…When fluid starts to move backward, the channel is blocked by the flap. For a better understanding of physics behind these check-valves, pneumatic micro-actuators and three-valve micropump are discussed and numerically simulated in several studies [17][18][19][20][21][22]. Although this fluidic diode tolerates a wide range of in-flow pressures, the diodic efficiency depends on the channel geometry, in-flow pressures, flow pattern, and the mechanical and physical properties of the flap structure.…”

Section: Introductionmentioning

confidence: 99%

A pneumatically controlled microfluidic rectifier enabling zero backflow under pulsatile flow regime

Bavil

Coltisor

Estlack

et al. 2021

J. Micromech. Microeng.

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A pulsatile microfluidic pump transports discrete volume to specific target locations. However, backflow in the pulsatile microfluidic pump often decreases the pumping efficiency and causes unwanted sample mixing due to unsteady boundaries. Employing the concept of a transistor, we developed a pneumatically controlled microfluidic rectifier (PCMR) that prevents backflow in the pulsatile flow regime. This PCMR was interconnected with a microfluidic pulsatile pumping system to characterize the functions of PCMR under continuous pumping sequences (CPS) and discrete pumping sequences (DPS) with various gate pressures on the PCMR. In the passive mode (zero gate pressure), 1.07% backflow for a DPS and 0.12% for a CPS were achieved. However, by adjusting the gate pressure on PCMR actively, we were able to achieve zero backflow for both pumping sequences at the cost of pumping efficiency. Interestingly, when the flow passes through the PCMR under the controlled gate-pressure, a fluidic oscillation was observed due to the force balance between the fluidic pressure and the gate-pressure. This microfluidic system successfully demonstrated half-rectification from various pulsatile flow profiles. By incorporating multiple three-microvalve systems in parallel with frequency modulation, a fully rectified flow pattern can be realized to enable steady laminar flow from pulsatile micropumps.

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Property Investigation of Replaceable PDMS Membrane as an Actuator in Microfluidic Device

Cited by 9 publications

References 55 publications

Field-Induced Transversely Isotropic Shear Response of Ellipsoidal Magnetoactive Elastomers

Field-Induced Transversely Isotropic Shear Response of Ellipsoidal Magnetoactive Elastomers

Effects of Flow‐Induced Microfluidic Chip Wall Deformation on Imaging Flow Cytometry

A pneumatically controlled microfluidic rectifier enabling zero backflow under pulsatile flow regime

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