2019
DOI: 10.22159/ijap.2019.v11s6.33534
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Prophylactic Antibiotics Alone Versus Combined Prophylaxis and Postoperative Antibiotics for Preventing Surgical-Site Infections Associated With Ear and Nose Reconstructive Surgery

Abstract: Objective: The aim of this study was to acquire supporting data for the rational use of antibiotics in plastic reconstructive surgery in the Ear-Nose-Throat/Head and Neck Surgery Department at Cipto Mangunkusumo Hospital–Faculty of Medicine Indonesia University. Methods: This pilot study, with a negative trial design, included 12 subjects who were randomly divided into two groups: preoperative prophylactic antibiotic-only group and a combination of prophylactic and postoperative antibiotic group (control… Show more

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Cited by 2 publications
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“…In addition, the hospital regulation by the Ministry of Health of the Republic of Indonesia Number 2406/MENKES/PER/XII/2011 regarding the general guidelines for the use of antibiotics also stated that first- and second-generation cephalosporins are recommended as surgical prophylaxis [ 41 , 42 ]. According to Koento and Saleh [ 43 ], the optimal time to provide a prophylactic antibiotic was 0–30 minutes before the incision. The risk of infection would increase if prophylactic antibiotics are administered > 30 minutes before or after the incision.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, the hospital regulation by the Ministry of Health of the Republic of Indonesia Number 2406/MENKES/PER/XII/2011 regarding the general guidelines for the use of antibiotics also stated that first- and second-generation cephalosporins are recommended as surgical prophylaxis [ 41 , 42 ]. According to Koento and Saleh [ 43 ], the optimal time to provide a prophylactic antibiotic was 0–30 minutes before the incision. The risk of infection would increase if prophylactic antibiotics are administered > 30 minutes before or after the incision.…”
Section: Discussionmentioning
confidence: 99%