Prophylactic antibiotics for third molar surgery

Piecuch, Joseph F.; Arzadon, Joseph M; Lieblich, Stuart E.

doi:10.1016/0278-2391(95)90502-2

Cited by 112 publications

(78 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Extensive studies of third molar removal in patients with fully or partial bony infection of third molars favour the use of prophylactic parenteral antibiotics, since lower postoperative infection rates have been reported. 5 Piecuch et al 5 in their study involving bony impacted third molars the use of preoperative parenteral antibiotics resulted in a significantly reduced post-operative infection rate. However, no advantage has been shown in soft tissue impaction alone.…”

Section: Parenteral Antibiotics Support For Their Use and Timingmentioning

confidence: 97%

“…Post-operative infection usually presents with dry socket and less commonly may manifest with severe fascial space involvement. 4 Factors which appear to be associated with post-operative infection include full or partial bony impaction, rather than the routine extraction of teeth, 5 and the presence of preoperative infection. 6 The reported incidence of postoperative infection varies between 1-12.6% [7][8][9][10][11][12][13][14][15][16][17][18] (Table 3) There was also variation in the reported rate of alveolar osteitis ranging from 1% to 6.3%.…”

Section: Complications After Third Molar Surgerymentioning

confidence: 99%

“…4 Factors which appear to be associated with post-operative infection include full or partial bony impaction, rather than the routine extraction of teeth, 5 and the presence of preoperative infection. 6 The reported incidence of postoperative infection varies between 1-12.6% [7][8][9][10][11][12][13][14][15][16][17][18] (Table 3) There was also variation in the reported rate of alveolar osteitis ranging from 1% to 6.3%. 16,[19][20] Post-operative complications and prophylactic antiobiotics There is a considerable volume of evidence that advocates antibiotics for the prevention of infection following third molar surgery.…”

Section: Complications After Third Molar Surgerymentioning

confidence: 99%

“…37 The timing of parenteral antibiotic prophylactic administration appears to be important. 17,37 When considering the analogy of surgical removal of third molars to 'clean-contaminated surgery' it is reasonable to assume that the optimal time for the administration of antibiotics is up to two hours preoperatively. 36,42 Thomas et al 43 after an audit of antibiotic prescribing practises suggested that preoperative parenteral antibiotics are unwarranted for routine third molar surgery in medically fit patients.…”

Section: Parenteral Antibiotics Support For Their Use and Timingmentioning

confidence: 99%

“…45 Antibiotic administration is not without risks including anaphylaxis, development of resistant bacteria and unjustified medical costs. 37,46 Other undesirable consequences include Hochwald et al 7 1.0 Rud 8 4.0 Curran et al 9 8.2 Goldberg et al 10 4.2 Osborne et al 11 3.4 Sisk et al 12 1.2 Mitchell et al 13 11.0 Happonen et al 14 11.8 Loucota 15 1-5.0 Chiapasco et al 16 1.5 Piecuch et al 17 3.5 Nordenram et al 18 12.6 OPINION the interaction with other medical products and therefore an indirect effect in the management of other medical conditions. Direct toxicity may affect the gastrointestinal tract with nausea, vomiting, diarrhoea and abdominal pain.…”

Section: Antibiotic Choice and Dose And Parenteral Prophylaxismentioning

confidence: 99%

See 4 more Smart Citations

Antibiotic prophylaxis and third molar surgery

Martin

Kanatas²,

Hardy³

2005

Br Dent J

View full text Add to dashboard Cite

show abstract

Section: Parenteral Antibiotics Support For Their Use and Timingmentioning

confidence: 97%

Section: Complications After Third Molar Surgerymentioning

confidence: 99%

Section: Complications After Third Molar Surgerymentioning

confidence: 99%

Section: Parenteral Antibiotics Support For Their Use and Timingmentioning

confidence: 99%

Section: Antibiotic Choice and Dose And Parenteral Prophylaxismentioning

confidence: 99%

See 3 more Smart Citations

Antibiotic prophylaxis and third molar surgery

Martin

Kanatas²,

Hardy³

2005

Br Dent J

View full text Add to dashboard Cite

show abstract

Clinical Decision Making in Restorative Dentistry, Endodontics, and Antibiotic Prescription

Zadik

Levin

2008

Journal of Dental Education

View full text Add to dashboard Cite

The purpose of this study was to evaluate the influence of geographic location of graduation (Israel, Eastern Europe, Latin America) on decision making regarding management of dental caries, periapical lesions, and antibiotic prescribing routines. A questionnaire was given to ninety-eight general practitioners regarding demographic and work habits. Photographs of lesions were shown on a screen. Participants reported recommended treatment and whether they would routinely prescribe antibiotics following regular endodontic treatment, retreatment, and impacted third molar surgical extraction in healthy patients. There was a 94 percent (n=92) response rate, of which eighty-five responses were used in the data analysis. Surgical treatment of asymptomatic enamel caries lesions was not recommended by most of the subjects, and surgery was recommended for DEJ caries lesions in low or moderate caries risk patients, both without significant differences between geographic regions of dental school graduation. Israelis had a lower frequency of retreatment in asymptomatic teeth that demonstrated periapical radiolucency with post restoration (without crown) compared to Latin Americans and East Europeans. Most of the participants would not retreat asymptomatic teeth that demonstrated periapical radiolucency with post and crown. After third molar surgery, 46 percent of participants routinely prescribed antibiotics. Significantly more Latin American graduates prescribed antibiotics following endodontic treatment, retreatment, and third molar extractions (p<0.05). Overmedication (antibiotics) and overtreatment (caries) among young practitioners reflect failure of undergraduate education in proper use of antibiotics and management of the carious lesions according to the patient's clinical presentation and caries risk assessment rather than routinely undertaking surgical caries treatment.

show abstract

Evaluation of optimal short‐term amoxicillin use for impacted lower third molar removal

Yamada

Kodama

Shingaki

et al. 2020

Oral Science International

View full text Add to dashboard Cite

Purpose Antibiotic use in impacted lower third molar removal is controversial, and surgical site infection (SSI) is a common postoperative complication. The purpose of this study was to evaluate the relationship between the duration of amoxicillin use and SSI in impacted lower third molar removal. Patients and Methods This was a retrospective study of patients who had more than one impacted lower third molar removed in the outpatient setting and were prescribed amoxicillin for less than 48 hours between January 2016 and December 2018. Patients were stratified by duration of antibiotic use. The primary outcome was the incidence of SSI. Other variables evaluated were demographics, pre‐ and post‐operative antibiotic use, pre‐ and intra‐operative variables, and tooth anatomy. Results In a total 907 separate operations, amoxicillin was given preoperatively within 24 hours of surgery in 84/430 cases (17.6%). SSI occurred in eight cases (0.88%). After adjusting for differences between the two groups that used preoperative amoxicillin within 24 hours or over 24 hours and used amoxicillin preoperatively or postoperatively, no significant difference was seen in SSI. Bivariate analysis showed that only deeply impacted third molars were significantly associated with the development of SSI. Conclusions The result in this study suggests that amoxicillin use within 24 hours is adequate for prevention of SSI after impacted lower third molar removal. When considering the risk factors of SSI in each case, it is necessary to use antibiotics for an appropriate duration.

show abstract

Prophylactic antibiotics for third molar surgery

Cited by 112 publications

References 22 publications

Antibiotic prophylaxis and third molar surgery

Antibiotic prophylaxis and third molar surgery

Clinical Decision Making in Restorative Dentistry, Endodontics, and Antibiotic Prescription

Evaluation of optimal short‐term amoxicillin use for impacted lower third molar removal

Contact Info

Product

Resources

About