Prophylactic antibiotics given within 24 hours of surgery, compared with antibiotics given for 72 hours perioperatively, increased the rate of methicillin-resistant Staphylococcus aureus isolated from surgical site infections

Kusachi, Shozo; Sumiyama, Yoshinobu; Nagao, Jirō; Arima, Yoichi; Yoshida, Yuichi; Tanaka, Hidenori; Nakamura, Yoichi; Saida, Yoshihisa; Watanabe, Manabu; Watanabe, Ryohei; Sato, Junko

doi:10.1007/s10156-007-0574-z

Cited by 17 publications

(10 citation statements)

References 26 publications

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“…Multiple-dose regimens of first-generation (cefazolin) or second-generation (cefotiam) cephalosporins of four days, operative day only, and three days in duration did not differ in overall SSI rates. 295 Recommendations. Antimicrobial prophylaxis in gastroduodenal procedures should be considered for patients at highest risk for postoperative infections, including risk factors such as increased gastric pH (e.g., patients receiving acid-suppression therapy), gastroduodenal perforation, decreased gastric motility, gastric outlet obstruction, gastric bleeding, morbid obesity, ASA classification of ≥3, and cancer.…”

Section: Gastroduodenal Proceduresmentioning

confidence: 98%

See 1 more Smart Citation

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Bratzler

Dellinger

Olsen

et al. 2013

American Journal of Health-System Pharmacy

1,887

1,464

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Section: Gastroduodenal Proceduresmentioning

confidence: 98%

“…292 Choice of agent. The most frequently used agents for gastroduodenal procedures were firstgeneration 271,273,277,278,284,[293][294][295][296][297] and second-generation 269,270,274,275,280,293,294,298 cephalosporins. No differences in efficacy between first-and secondgeneration cephalosporins were found.…”

Section: Gastroduodenal Proceduresmentioning

confidence: 99%

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Bratzler

Dellinger

Olsen

et al. 2013

American Journal of Health-System Pharmacy

1,887

1,464

View full text Add to dashboard Cite

“…Choice of agent. The most frequently used agents for gastroduodenal procedures were first-generation [271,273,277,278,284,[293][294][295][296][297] and second-generation [269,270,274,275,280,293,294,298] cephalosporins. No differences in efficacy between first-and second-generation cephalosporins were SURGICAL PROPHYLAXIS GUIDELINES found.…”

Section: Efficacymentioning

confidence: 99%

Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery

Bratzler

Dellinger

Olsen

et al. 2013

Surgical Infections

1,204

1,225

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T hese guidelines were developed jointly by the American Society of Health-System Pharmacists (ASHP), the Infectious Diseases Society of America (IDSA), the Surgical Infection Society (SIS), and the Society for Healthcare Epidemiology of America (SHEA). This work represents an update to the previously published ASHP Therapeutic Guidelines on Antimicrobial Prophylaxis in Surgery [1], as well as guidelines from IDSA and SIS [2,3]. The guidelines are intended to provide practitioners with a standardized approach to the rational, safe, and effective use of antimicrobial agents for the prevention of surgical site infections (SSIs) based on currently available clinical evidence and emerging issues. Prophylaxis refers to the prevention of an infection and can be characterized as primary prophylaxis, secondary prophylaxis, or eradication. Primary prophylaxis refers to the prevention of an initial infection. Secondary prophylaxis refers to the prevention of recurrence or reactivation of a preexisting infection. Eradication refers to the elimination of a colonized organism to prevent the development of an infection. These guidelines focus on primary perioperative prophylaxis. Guidelines development and use Members of ASHP, IDSA, SIS, and SHEA were appointed to serve on an expert panel established to ensure the validity, reliability, and utility of the revised guidelines. The work of the panel was facilitated by faculty of the

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“…7 In that study, the patients in the present study with gastric cancer and colorectal cancer were partly represented. We previously reported that although there were no differences in the incidence of SSI between the single-day dosage and the 3-day dosages of CEZ and CTM, the isolation rates of both methicillin-sensitive Staphylococcus aureus (MSSA) and MRSA from the infection focus showed that developed SSIs were higher in a single-day dosage, and MRSA was considered to be induced from MSSA by postoperative prophylactic antibiotics.…”

Section: Discussionmentioning

confidence: 99%