Prophylactic Antibiotics in Endoscopic Sinus Surgery: A Short Follow-Up Study

Abstract

The use of an antibiotic (amoxicillin/clavulanate) in the postoperative period is able to improve the outcome in the early blood crust healing phase: nasal obstruction and drainage are reduced and the endoscopic score objectively showed a faster recovery.

Endoscopic Monitoring of Postoperative Sinonasal Mucosa Wounds Healing

“…2008). The use of an antibiotic (amoxicillin/clavulanate) in the postoperative period is able to improve the outcome in the early blood crust healing phase: nasal obstruction and drainage are reduced and the endoscopic score objectively showed a faster recovery (Albu S. 2010). Patients recover in 9 to 10 days after ESS when provided with appropriate pain management.…”

Common harms from amoxicillin: a systematic review and meta-analysis of randomized placebo-controlled trials for any indication

“…The result was not significant for the subgroup of studies involving amoxicillin alone. The NNH for candidiasis was 27 (95% CI [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42]. In addition to explicit candidiasis, one trial reported rates of diaper rash of about 50% among infants treated with amoxicillin-clavulanic acid.…”

The role of antibiotics in endoscopic sinus surgery

“…Three years later, Liang et al [17] showed that there was no difference amongst patients treated with Chinese herbal medicine, amoxicillin, or placebo in the postoperative period in the Chinese version of the Rhinosinusitis Outcome Measure (CRSOM-31) and endoscopic scores. On the contrary, in 2010, Albu and Lucaciu [18] were able to show improved endoscopic scores on postoperative day number 5 and 12 with postoperative antibiotic treatment.…”