Prophylactic oophorectomy in ovarian cancer prevention

Abstract

We recommend bilateral oophorectomy for all women with a positive family history of ovarian carcinoma and for all women undergoing hysterectomy after the age of 40. The decision for prophylactic oophorectomy as a complementary procedure to other indicated gynecologic surgeries should depend on the individual patient and her ability to comply with lifelong estrogen replacement therapy.

Role of prophylactic oophorectomy at the time of hysterectomy in ovarian cancer prevention in Thailand

“…A study from Japan reported that an estimated 3.2% and 2.2% reduction in ovarian cancer incidence would be achieved if routine prophylactic removal of ovaries were performed in women who underwent hysterectomy at age >40 and >45, respectively 9 . Many authorities have recommended that prophylactic oophorectomy be performed during benign pelvic/abdominal surgery for women >40 or >45 years of age 8,10 , 11 . However, in Thailand, the incidence of ovarian cancer is 4.7 per 100 000 which is much lower than those in the developed world 12 .…”

Auftreten eines serös-papillären Adenokarzinoms mit Müllerscher Neoplasie nach prophylaktischer Ovarektomie

“…Als weiterer zu beachtender Aspekt bei der Entscheidung zur prophylaktischen Ovarektomie bei makroskopisch unauffälligen Ovarien ist die -besonders bei jünge-ren Frauen -resultierende langjährig notwendige Hormonsubstitution mit ihren Kosten, Risiken und mögli-chen Compliance-Problemen der betroffenen Frauen [9,10].…”

Synchronous Primary Ovarian and Endometrial Carcinomas

“…[3][4] The endometroid type of carcinoma is the most frequent.4-8 The histologie classification of these tumors is straightforward when they are of the same origin and controversial when they are of different types. [9][10][11][12][13][14][15][16][17][18] The purpose of this study was to evaluate the treatment and postoperative follow-up of patients with coexisting primary ovarian and endometrial carcinomas.…”