Prophylactic Postoperative Antibiotics May Not Reduce Pin Site Infections after External Fixation

Abstract

Our randomized data do not suggest that oral antibiotics alter the incidence, timing, or severity of pin infection. This study does not support the use of prophylactic oral antibiotics in healthy patients.

A Comparison of Femoral Lengthening Methods Favors the Magnetic Internal Lengthening Nail When Compared with Lengthening Over a Nail

“…External fixation has provided the stability and adjustability needed for successful femoral bone lengthening [5,14,26]. However, reliable, external fixation has been marred by patient dissatisfaction with pin site pain (and need for extended opioid use), infection (and antibiotic-related complications) [6,8,15], knee stiffness [2,12,16,21], and the need for clothing modification [22]. The lengthening over a nail (LON) technique [29] was introduced to reduce the time patients needed to wear the external fixator by combining the simultaneous use of internal and external fixation, a concept called Bintegrated fixation^ [1].…”

Research in Fracture Healing and Its Clinical Applications in the Veterinary Practice

“…Due to the pin fixation the protective shell of the skin is disrupted and the pin channels offer an entry point for pathogens. Pin channel infections have been reported to occur in more than 50% of cases [32]. A thorough treatment with antibiotics and antimicrobial solutions resolves this side effect in most cases.…”

Treatment Options for Pin Site Infection during Kirschner Wires in Elective Forefoot Surgery

“…The third one is associated with cleaning solutions that also played a major role to reduce the infection risk like its chlorhexidine might be helpful to decrease the colonization of pin site [4]. There is a need to make certain improvements in the surgical instruments and anti-biotics to significantly overcome the infection rate, and oral antibiotics are the best options to resolve such infection rate [41].…”

“…Also, Fragomen Austin and others majorly worked on exaggerating the working of prophylactic postoperative antibiotics and its implications that might not significantly reduce the pin site infection after the external fixation.They concluded that there is no clear difference between antibiotics and nonantibiotics treatment groups, especially in the pin site infection case in the postoperative surgical situation. According to them, there is a need to make certain improvements in the surgical instruments and anti-biotics to significantly overcome the infection rate, and oral antibiotics are the best options to resolve such infection rate[41]. This kind of treatment option was also mentioned by DimitriCeroni and others in the journal of children's orthopedics where they majorly studied the prevention of pin-tract infection by using the osteomyelitis based treatment during the pediatric external fixation.…”