Propofol for procedural sedation in the emergency department

Abstract

Propofol is effective and safe for procedural sedation in the ED. Propofol has a considerably shorter duration of action than midazolam, thereby shortening the period of sedation.

Pre-procedural fasting for coronary interventions: is it time to change practice?

“…Similarly, in an observational study by Dunn et al 12 of 48 non-fasting patients using Propofol, no patient developed pulmonary aspiration. A Cochrane review of 38 randomised controlled trials did not show an increased risk of pulmonary aspiration with shorter fluid fast 13…”

The use of propofol for procedural sedation and analgesia in the emergency department: a comparison with midazolam

“…Cheol et al ,10 who conducted a randomised double blind comparative study using propofol alone and combined propofol and midazolam in colonoscopy, found that both propofol alone and combined propofol and midazolam are safe and effective. A combination of propofol and midazolam on the other hand is judged more effective than using propofol alone in producing sedation without significant adverse effects 11 12…”

Sedation for oocyte retrieval using target controlled infusion of propofol and incremental alfentanil delivered by non‐anaesthetists

“…Accident and emergency (A&Es) departments continue to draw inferences of 'safety' after describing sedation with propofol in limited numbers (without reference to 95% CI) and with little emphasis on maintaining verbal contact [16,17]. The Academy of Royal Colleges document on safe sedation practice, led by the Royal College of Anaesthetists but with members from all relevant specialties including the Faculty of Accident & Emergency Medicine, is very clear on this topic.…”