Propofol infusion technique for outpatient general anesthesia

Candelaria, Lionel M; Smith, R.Kuhen

doi:10.1016/0278-2391(95)90385-2

Cited by 27 publications

(8 citation statements)

References 16 publications

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“…Furthermore, the initial loading dose of propofol in our patients was similar to the loading doses used by other studies that report emergence within 20-25 min of discontinuing propofol. [12][13][14][15] To the best of our knowledge, this has not been reported previously.…”

Section: Discussioncontrasting

confidence: 56%

Delayed awakening in dystonia patients undergoing deep brain stimulation surgery

Trombetta

Deogaonkar

et al. 2010

Journal of Clinical Neuroscience

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Section: Discussioncontrasting

confidence: 56%

Delayed awakening in dystonia patients undergoing deep brain stimulation surgery

Trombetta

Deogaonkar

et al. 2010

Journal of Clinical Neuroscience

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“…Dose and rate dependent ventilatory depression is also associated with propofol. However neither hypotension nor apnea requiring intervention generally occurs with doses normally used in ambulatory office anesthesia for oral and maxillofacial surgical procedures [7,8].…”

Section: Propofolmentioning

confidence: 99%

Comparitive Evaluation of Propofol and Midazolam as Conscious Sedatives in Minor Oral Surgery

Keerthy

Balakrishna

Srungeri

et al. 2014

J. Maxillofac. Oral Surg.

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Objective The objective of the study was to assess the efficacy of propofol and midazolam as an intravenous sedative agent in minor oral surgical procedures in terms of: (a) the onset of action, (b) heart rate, (c) oxygen saturation, (d) systolic and diastolic blood pressure, (e) respiratory rate, (f) pain during the injection of sedative agent, (g) recovery period, (h) side effects, (i) patient's cooperation during the surgery. Methodology This was a double blind randomized study in which one group of 20 patients received propofol with the induction dose of 0.5 mg/kg and 50 lg/kg/min which was administered by syringe infusion pump as a maintenance dose and the other group received midazolam in a single dose of 75 lg/kg and no maintenance dose was given, instead 5 % dextrose was administered by syringe infusion pump at the rate of 50 lg/kg/min. Since propofol was milky white in colour, a green cloth was covered over the infusion pump in all cases. The surgeon, assistants and observers were blind about the medications which would be given to the patient for sedation. After the administration of the sedative, local anesthesia was achieved with 2 % lignocaine hydrochloride. Results The onset of action in propofol group was significant as onset of action was faster. The maximum increase in heart rate in propofol group was at 10 min intraoperatively (Mean ± 80.40 ± 12.73) and that in midazolam group was at 15 min intraoperatively (Mean 79.25 ± 13.44). Post operatively the heart rate decreased near to the baseline value in both the groups. The average oxygen saturation before induction in propofol group was 99.7 ± 0.73 % and that of midazolam group was 99.15 ± 01.31 P = 0.314. None of the patients in this study developed apnea. The systolic blood pressure (Mean ± SD) before induction in both the groups decreased from the baseline value after the administration of sedatives. The diastolic blood pressure (Mean ± SD) before induction in both the groups decreased from the baseline value after the administration of sedatives and the decreased diastolic blood pressure was maintained throughout the procedure. The respiratory rate (Mean ± SD) before induction in both the groups decreased from the baseline value after the administration of sedatives. The decreased respiratory rate remained throughout the surgical procedure. Pain during the injection of the sedatives was reported by nine patients (45 %) in the propofol group whereas none of the patients in midazolam group complained of pain during the injection. This is statistically significant (P = 0.001). The recovery time (Mean ± SD) in propofol group was 22.50 ± 3.04 (range 15-25 min) and that in midazolam group was 33.75 ± 3.93 (range 30-40 min), which was statistically significant (P \ 0.001). Patients in the propofol group were significantly less co-operative than midazolam group at both 10 and 25 min intra operatively. Conclusion The design of the present study permitted qualitative assessment of propofol and midazolam as sedative agents in minor oral surgical ...

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“…7. Admit the patient on the morning of the surgery, bring to the operating room, and induce under general anesthesia 26,27 . 8.…”

Section: Introductionmentioning

confidence: 99%

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

McGovern

Ratneswaren

Smith

et al. 2015

JoVE

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Stereotactic Electroencephalography (SEEG) is a technique used to localize seizure foci in patients with medically intractable epilepsy. This procedure involves the chronic placement of multiple depth electrodes into regions of the brain typically inaccessible via subdural grid electrode placement. SEEG thus provides a unique opportunity to investigate brain function. In this paper we demonstrate how SEEG can be used to investigate the role of the dorsal anterior cingulate cortex (dACC) in cognitive control. We include a description of the SEEG procedure, demonstrating the surgical placement of the electrodes. We describe the components and process required to record local field potential (LFP) data from consenting subjects while they are engaged in a behavioral task. In the example provided, subjects play a cognitive interference task, and we demonstrate how signals are recorded and analyzed from electrodes in the dorsal anterior cingulate cortex, an area intimately involved in decision-making. We conclude with further suggestions of ways in which this method can be used for investigating human cognitive processes. Video LinkThe video component of this article can be found at

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Propofol infusion technique for outpatient general anesthesia

Cited by 27 publications

References 16 publications

Delayed awakening in dystonia patients undergoing deep brain stimulation surgery

Delayed awakening in dystonia patients undergoing deep brain stimulation surgery

Comparitive Evaluation of Propofol and Midazolam as Conscious Sedatives in Minor Oral Surgery

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

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