Propofol und postoperative Übelkeit und/oder Erbrechen

Jost, U; Dörsing, C; Jahr, Craig E.; Hirschauer, M.

doi:10.1007/s001010050468

Cited by 15 publications

(6 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…But this fact can also be due to underpowered small groups and could be of interest in further research on this topic. When intravenous anesthetics were used, PONV rates in the control group were as low as expected [18]. However, in the obese group, intravenous anesthetics were not able to prevent or reduce nausea and vomiting.…”

Section: Discussionmentioning

confidence: 82%

Postoperative nausea and vomiting in bariatric surgery in comparison to non-bariatric gastric surgery.

Groene¹,

Eisenlohr²,

Zeuzem³

et al. 2018

Videosurgery and Other Miniinvasive Techniques

View full text Add to dashboard Cite

IntroductionPostoperative nausea and vomiting (PONV) are complications of general anesthesia. Patient-specific factors, type of surgery and a variety of drugs determine the frequency. Clinical experience shows nausea and vomiting to be very frequent in morbidly obese patients undergoing bariatric surgery.AimTo detect the onset and extent of nausea and vomiting in the group of morbidly obese patients undergoing laparoscopic bariatric surgery.Material and methodsWe conducted a retrospective data bank analysis (since 2004) of all patients with body mass index > 35 kg/m2 undergoing laparoscopic bariatric surgery in comparison to patients with a body mass index < 35 kg/m2 undergoing gastric surgery. Propensity score matching was applied to minimize bias effects. The frequency of postoperative nausea was defined as the primary outcome parameter.ResultsOne hundred and thirty-eight patients were included. There was a significant difference between the morbidly obese group and the control group concerning the frequency of postoperative nausea (15.9% vs. 55.1%; p < 0.001). In patients receiving volatile anesthetics a significant difference between groups concerning frequency of PONV was not observed. Intravenous anesthetics were suitable to reduce PONV in the control group but not in the morbidly obese group (12.5% vs. 56.8%, p < 0.001). With given prophylaxis PONV events still occurred in 15.6% vs. 48.8% (p = 0.003).ConclusionsMorbidly obese patients undergoing laparoscopic bariatric surgery are at higher risk of suffering from PONV than non-morbidly obese patients. To reduce the PONV incidence in morbidly obese patients, further research, especially focusing on more efficient use of antiemetic drugs, seems to be necessary.

show abstract

Section: Discussionmentioning

confidence: 82%

Postoperative nausea and vomiting in bariatric surgery in comparison to non-bariatric gastric surgery.

Groene¹,

Eisenlohr²,

Zeuzem³

et al. 2018

Videosurgery and Other Miniinvasive Techniques

View full text Add to dashboard Cite

show abstract

“…It has been previously shown not only that the TIVA might be effective in lowering 5-HT3 levels in the area postrema but also that subhypnotic doses of propofol are effective in decreasing the incidence of PONV [20,21]. Previous studies have evaluated the anti-emetic efficacy of propofol in maintaining the anesthesia in patients who are scheduled to undergo thyroidectomy [2,22,23]. Sonner et al [2] and Jost et al [22] demonstrated that the incidence of PONV was significantly lower in patients receiving propofol for the maintenance of anesthesia as compared with those doing isoflurane.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have evaluated the anti-emetic efficacy of propofol in maintaining the anesthesia in patients who are scheduled to undergo thyroidectomy [2,22,23]. Sonner et al [2] and Jost et al [22] demonstrated that the incidence of PONV was significantly lower in patients receiving propofol for the maintenance of anesthesia as compared with those doing isoflurane.…”

Section: Discussionmentioning

confidence: 99%

Postoperative nausea and vomiting after total thyroidectomy: sevoflurane combined with prophylactic ramosetron vs. propofol-based total intravenous anesthesia

Park

Lee

Jeong

et al. 2014

Korean J Anesthesiol

View full text Add to dashboard Cite

BackgroundThe frequent and distressing adverse events (AEs) of postoperative nausea and vomiting (PONV) are of major concern in 63-84% of adult patients undergoing thyroidectomy. We conducted this prospective study to compare two prophylactic strategies; sevoflurane combined with ramosetron and propofol-based total intravenous anesthesia in a homogenous group of non-smoking women undergoing total thyroidectomy.MethodsIn the current prospective study, we enrolled a consecutive series of 64 female patients aged between 20 and 65 years with an American Society of Anesthesiologists physical status of I or II who were scheduled to undergo elective total thyroidectomy under general anesthesia. Patients were randomized to either the SR (sevoflurane and remifentanil) group or the TIVA group. We evaluated the incidence and severity of PONV, the use of rescue anti-emetics and the severity of pain during the first 24 h after surgery.ResultsThere were no significant differences in the proportion of the patients with a complete response and the Rhodes index, including the occurrence score, distress score and experience score, between the two groups. In addition, there were no significant differences in the proportion of the patients who were in need of rescue anti-emetics or analgesics and the VAS scores between the two groups.ConclusionsIn conclusion, TIVA and ramosetron prophylaxis reduced the expected incidence of PONV in women undergoing total thyroidectomy. In addition, there was no significant difference in the efficacy during the first 24 h postoperatively between the two prophylactic regimens.

show abstract

“…Even after prolonged administration, patients recover rapidly [ 13 ]. Several studies have reported that it causes a lower incidence of nausea and vomiting following surgery [ 14 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

Usefulness of Intravenous Anesthesia Using a Target-controlled Infusion System with Local Anesthesia in Submuscular Breast Augmentation Surgery

Chung

Cha²,

Lee

et al. 2012

Arch Plast Surg

View full text Add to dashboard Cite

BackgroundPatients have anxiety and fear of complications due to general anesthesia. Through new instruments and local anesthetic drugs, a variety of anesthetic methods have been introduced. These methods keep hospital costs down and save time for patients. In particular, the target-controlled infusion (TCI) system maintains a relatively accurate level of plasma concentration, so the depth of anesthesia can be adjusted more easily. We conducted this study to examine whether intravenous anesthesia using the TCI system with propofol and remifentanil would be an effective method of anesthesia in breast augmentation.MethodsThis study recruited 100 patients who underwent breast augmentation surgery from February to August 2011. Intravenous anesthesia was performed with 10 mg/mL propofol and 50 µg/mL remifentanil simultaneously administered using two separate modules of a continuous computer-assisted TCI system. The average target concentration was set at 2 µg/mL and 2 ng/mL for propofol and remifentanil, respectively, and titrated against clinical effect and vital signs. Oxygen saturation, electrocardiography, and respiratory status were continuously measured during surgery. Blood pressure was measured at 5-minute intervals. Information collected includes total duration of surgery, dose of drugs administered during surgery, memory about surgery, and side effects.ResultsIntraoperatively, there was transient hypotension in two cases and hypoxia in three cases. However, there were no serious complications due to anesthesia such as respiratory difficulty, deep vein thrombosis, or malignant hypertension, for which an endotracheal intubation or reversal agent would have been needed. All the patients were discharged on the day of surgery and able to ambulate normally.ConclusionsOur results indicate that anesthetic methods, where the TCI of propofol and remifentanil is used, might replace general anesthesia with endotracheal intubation in breast augmentation surgery.

show abstract

Propofol und postoperative Übelkeit und/oder Erbrechen

Cited by 15 publications

References 24 publications

Postoperative nausea and vomiting in bariatric surgery in comparison to non-bariatric gastric surgery.

Postoperative nausea and vomiting in bariatric surgery in comparison to non-bariatric gastric surgery.

Postoperative nausea and vomiting after total thyroidectomy: sevoflurane combined with prophylactic ramosetron vs. propofol-based total intravenous anesthesia

Usefulness of Intravenous Anesthesia Using a Target-controlled Infusion System with Local Anesthesia in Submuscular Breast Augmentation Surgery

Contact Info

Product

Resources

About