Proportions of Pre-Cancerous Cervical Lesions and Its Associated Factors among Women Clients in the Age Group of 30-49yrs in Gynecology Ward of Dessie Referral Hospital and FGAE, North-East Ethiopia, 2016

Temesgen, Kibir; Workie, Amare; Dilnessa, Tenagnework; Abate, Mengistu

doi:10.9734/jcti/2019/v9i230105

Cited by 12 publications

(15 citation statements)

References 5 publications

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“…Moreover, our findings are also in line with other studies. 15 , 25 , 32 , 37 , 41 , 43 Having multiple sexual partners increases the likelihood of acquiring HPV infection and in turn cervical cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Data were collected using a pretested structured questionnaire prepared by reviewing related studies, with modifications in line with the objectives of this particular study. 12 , 15–17 Two days of training on data-collection procedures was given for data collectors. Six BSc-qualified nurses certified in cervical screening and working in the gynecology ward in selected hospitals were assigned to collect the data, and the principal investigator supervised data collection.…”

Section: Methodsmentioning

confidence: 99%

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Precancerous Lesions of the Cervix and Associated Factors among Women of East Gojjam, Northwest Ethiopia, 2020

getinet¹,

Taye²,

Ayinalem³

et al. 2021

CMAR

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Background Cervical cancer is the commonest cancer of women’s reproductive system, and is caused by a progression of precancerous lesions of the cervix. Studies on the prevalence and associated factors of precancerous lesions of the cervix are very limited in Ethiopia, particularly in the study area. Objective This study aimed to assess precancerous lesions of the cervix and associated factors among women of East Gojjam, northwest Ethiopia in 2020. Methods A facility-based cross-sectional study was conducted on 340 cervical cancer–screened women in three hospitals of East Gojjam from February to April 2020. Data were collected by six BSc-qualified nurses who were working in the selected hospitals. EpiData Manager and SPSS 26 were used for data management and analysis. After the data had been clean, descriptive analysis was done and multivariate logistic regression used to identify predictors of precancerous lesions of the cervix. Statistical significance was taken to be P <0.05. Results Of the 340 recruited women, 15.3% (95% CI 11.83%–19.54%) had precancerous cervical lesions. Mean age was 37.11±9.3 years. Age 46–55 (AOR 3.8, 95% CI 1.21–12.47) years, age 56–65 (AOR 12.26, 95% CI 3.18–47.18) years, residing rurally (AOR 2.04, 95% CI 1.12–3.7), prolonged use of oral contraceptive pills (AOR 9.11, 95% CI 1.14–72.8), history of sexual transmitted infection (STI; AOR 3.40, 95% CI 1.32–8.78), HIV-positive status (AOR 4.89, 95% CI 1.54–15.49), and number of lifetime sexual partners (AOR 9.87, 95% CI 1.38–70.4) were important factors associated with precancerous lesions of the cervix. Conclusion We found relatively high prevalence of precancerous cervical lesions. Age, rural residence, prolonged use of oral contraceptives, STI, multiple sexual partners, and being HIV-positive were important factors associated with precancerous cervical lesions. Women aged >46 years, with a history of STI, being HIV infected, and with a history of multiple sexual partners should be encouraged to get screened for cervical cancer.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Precancerous Lesions of the Cervix and Associated Factors among Women of East Gojjam, Northwest Ethiopia, 2020

getinet¹,

Taye²,

Ayinalem³

et al. 2021

CMAR

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“…Hence, we used a DerSimonian and Laird random effects model [ 48 , 49 ] to estimate the pooled prevalence of precancerous cervical lesion. Studies that showed the largest weight were Plezer et al [ 37 ] that showed 6.35, Kebede et al [ 34 ] with 6.11, Temesgen et al [ 42 ] with 6.10, and Belayneh et al [ 28 ] that showed 6.80 weight, whereas Birara et al showed a relatively smaller weight which was 5.62 (Fig. 3 ).…”

Section: Resultsmentioning

confidence: 99%

“…Five studies were included from the Southern Nations Nationalities and People Region (SNNPR) [ 30 , 32 , 38 , 39 , 41 ]. In addition, five studies were included from the Amhara region [ 27 , 28 , 31 , 33 , 42 ]. The remaining two articles were from Oromia [ 43 ] and Tigray [ 34 ].…”

Section: Resultsmentioning

confidence: 99%

Precancerous cervical lesion in Ethiopia: systematic review and meta-analysis

et al. 2021

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Background Though cervical cancer is largely preventable, it is still the second most common female cancer globally and the leading cause of cancer deaths among females in African. Though many efforts have been done to study the burden of the disease in Ethiopia, primary studies examining the prevalence of precancerous cervical lesions are fragmented. Hence, this systematic review and meta-analysis is aimed at estimating the pooled prevalence of precancerous cervical lesion and its trends in Ethiopia. Methods This systematic review and meta-analysis was conducted using the following electronic databases. PubMed, Web of Science, SCOPUS, Science Direct, Google Scholar, African Index Medicus (AIM), African Journals Online databases, and Addis Ababa and Bahir Dar Universities research repositories were searched following the Preferred Items for Systematic Review and Meta-analysis (PRISMA) Guideline. STATA 15 statistical software was used to analyze the data. The quality of the included studies was assessed using the Joanna Briggs Institute (JBI) quality appraisal tool for meta-analysis. Heterogeneity between studies was assessed using the Cochrane Q test and I2 test statistics based on the random effects model. A random effects model was computed to estimate the pooled prevalence of precancerous cervical lesion in Ethiopia. Finally, the trend of precancerous cervical lesion in the country was presented. Result Seventeen studies with a total of 26,112 participants were included in the analysis. The pooled prevalence of precancerous cervical lesion was 15.16 (95% CI 10.16–19.70). The subgroup analysis by region showed the highest prevalence of precancerous cervical lesion at the Southern Nations and Nationalities Peoples Region (19.65%; 95% CI 15.51–23.80). The trend of precancerous cervical lesion prevalence showed an increased pattern over time. Conclusion Approximately one among six of the study participants had precancerous cervical lesion. The trend also showed that there is still an increasing precancerous cervical lesion in Ethiopia. Best practices in achieving high vaccination coverage shall be informed by practices in other successful countries.

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“…In Ethiopia, different studies were conducted to determine the prevalence and factors associated with precancerous lesions of the cervix. These studies reported that the prevalence of precancerous lesions among women ranges from 6.7% to 27.7% [ 10 – 21 ]. The common factors reported by the studies were early initiations of first sexual intercourse, multiple sexual partners, and a history of STI [ 11 , 12 , 14 , 16 , 17 , 19 – 23 ].…”

Section: Introductionmentioning

confidence: 99%

Precancerous lesions of the cervix and its determinants among Ethiopian women: Systematic review and meta-analysis

Tsehay

Afework

2020

PLoS ONE

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Introduction Precancerous lesions of the cervix are changes in cervical cells that make them more likely to develop into cancer. Understanding the prevalence and determinants of the precancerous lesions of the cervix among women helps to take an action like vaccination programs, improving screening coverage, and close management and follow-up which could decrease the morbidity and mortality caused by cervical cancer. Materials and methods The international databases, PubMed/MEDLINE, Web of Science, EMBASE, CINAHL, Google Scholar, Science Direct and Cochrane Library and unpublished reports were systematically searched. Two authors independently extracted all necessary data using a standardized data extraction format. STATA 14 statistical software was employed to analyse the data. The Cochrane Q test statistics and I 2 tests were used to assess the heterogeneity between the studies. A random-effect model was computed to estimate the pooled prevalence of precancerous lesions of the cervix in Ethiopia. Determinants of the precancerous lesion of cervix (early initiation of sexual intercourse, multiple sexual partners, and history of sexually transmitted infection) were analysed. Results Thirteen studies fulfilled the inclusion criteria and included in the meta-analysis. The I 2 test result showed high heterogeneity (I2, 93.2%, p = <0.001). Using the random effect analysis, the pooled prevalence of precancerous lesions of the cervix among women in Ethiopia was 14.21% (95% CI (10.49, 17.94). After adjusting of publication bias using trim-and-fill method, the pooled prevalence was 9.43% (95% CI (5.23, 13.62). Women who had multiple sexual partners in their lifetime (OR:2.67 CI: 1.49,4.79) and had a history of sexually transmitted infections (OR:6.22 CI: 2.99,12.92) were more likely to have a precancerous lesion of the cervix. Conclusion The pooled prevalence of the precancerous lesions of the cervix among Ethiopian women was 9.43%. It was associated with having multiple sexual partners and a history of sexually transmitted infections.

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Proportions of Pre-Cancerous Cervical Lesions and Its Associated Factors among Women Clients in the Age Group of 30-49yrs in Gynecology Ward of Dessie Referral Hospital and FGAE, North-East Ethiopia, 2016

Cited by 12 publications

References 5 publications

Precancerous Lesions of the Cervix and Associated Factors among Women of East Gojjam, Northwest Ethiopia, 2020

Precancerous Lesions of the Cervix and Associated Factors among Women of East Gojjam, Northwest Ethiopia, 2020

Precancerous cervical lesion in Ethiopia: systematic review and meta-analysis

Precancerous lesions of the cervix and its determinants among Ethiopian women: Systematic review and meta-analysis

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