Proposed New Strain of Canine
            <i>Kobuvirus</i>
            from Fecal Samples of Brazilian Domestic Dogs

Barros, Bruno de Cássio Veloso de; Castro, Ceyla Maria Oeiras de; Pereira, Diego; Ribeiro, Laila Graziela; Júnior, José Wandilson Barboza Duarte; Casseb, Samir Mansour Moraes; Holanda, Gustavo Moraes; Cruz, Ana Cecília Ribeiro; Júnior, Edivaldo Costa Sousa; Mascarenhas, Joana D’Arc Pereira

doi:10.1128/mra.01292-18

Cited by 5 publications

(3 citation statements)

References 14 publications

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“…Aichivirus A is divided in six types: human Aichi virus (AiV) (Yamashita et al 1991), canine kobuvirus (Kapoor et al 2011;Barros et al 2019), murine kobuvirus (Phan et al 2011), Kathmandu sewage kobuvirus (Ng et al 2012), roller kobuvirus (Pankovics et al 2014) and feline kobuvirus (Chung et al 2013). The other species also display a certain degree of variability, 3 types having been described in Aichivirus B, and 2 types in the species Aichivirus C, Aichivirus D and Aichivirus F. Finally, three genotypes (Fig.…”

Section: History and Taxonomymentioning

confidence: 99%

A Comprehensive Review on Human Aichi Virus

Rivadulla

Romalde

2020

Virol. Sin.

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Although norovirus, rotavirus, adenovirus and Astrovirus are considered the most important viral agents transmitted by food and water, in recent years other viruses, such as Aichi virus (AiV), have emerged as responsible for gastroenteritis outbreaks associated with different foods. AiV belongs to the genus Kobuvirus of the family Picornaviridae. It is a virus with icosahedral morphology that presents a single stranded RNA genome with positive sense (8280 nucleotides) and a poly (A) chain. AiV was first detected from clinical samples and in recent years has been involved in acute gastroenteritis outbreaks from different world regions. Furthermore, several studies conducted in Japan, Germany, France, Tunisia and Spain showed a high prevalence of AiV antibodies in adults (between 80% and 99%), which is indicative of a large exposure to this virus. The aim of this review is to bring together all the discovered information about the emerging pathogen human Aichi virus (AiV), discussing the possibles routes of transmission, new detection techniques and future research. Although AiV is responsible for a low percentage of gastroenteritis outbreaks, the high seroprevalence shown by human populations indicates an evident role as an enteric agent. The low percentage of AiV detection could be explained by the fact that the pathogen is more associated to subclinical infections. Further studies will be needed to clarify the real impact of AiV in human health and its importance as a causative gastroenteritis agent worldwide.

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Section: History and Taxonomymentioning

confidence: 99%

A Comprehensive Review on Human Aichi Virus

Rivadulla

Romalde

2020

Virol. Sin.

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“…In Brazil, CaKV was detected in multiple tissues of a puppy with clinical signs of gastroenteritis resulting in the first reported occurrence of extraintestinal CaKV in dogs [21]. The occurrence of other kobuviruses species have been reported in diarrheic fecal samples from pig and cattle in Brazil [19,20], and there is only one study reporting a strain of CaKV found in fecal samples of nondiarrheic dogs in the country [2].…”

Section: Introductionmentioning

confidence: 99%

Detection of canine kobuvirus RNA in diarrheic fecal samples of dogs with parvoviruses

et al. 2019

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Canine kobuvirus (CaKV) is a member of the Picornaviridae family and the Kobuvirus genus. CaKV was first described in fecal samples from diarrheic dogs in the USA in 2011, with subsequent reports in the UK, Italy, South Korea, China, Tanzania, and Japan. CaKV is frequently identified in feces of animals with or without clinical signs of gastroenteritis. The present study investigated the presence of CaKV in fecal samples from 53 diarrheic dogs from Londrina, southern Brazil. Using a RT-PCR assay, CaKV RNA was identified in three dogs, resulting in an overall occurrence rate of 5.7%. In addition, coinfection with canine parvovirus subtype 2b was detected in all CaKV-positive diarrheic fecal samples. Using a phylogenetic analysis based on the VP1 gene sequence, the Brazilian CaKV field strains were found to be very similar to a previously identified CaKV strain from Brazil that was found in the tissue of a puppy and were also found to be clustered with other CaKV strains detected worldwide and other kobuvirus strains identified in mouse, feline, and human hosts.

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“…Canine enteric coronavirus and canine distemper virus, as well as other low-prevalence agents (such as bocavirus, astrovirus, and kobuvirus), have been detected in dogs with enteric diseases worldwide (BARROS et al, 2019;BODEWES et al, 2014;CHOI et al, 2014;DOWGIER et al, 2017;LI et al, 2011). Although, we have not observed characteristic/pathognomonic intestinal lesions associated with these agents, we cannot completely rule out their involvement in some cases.…”

Section: Discussionmentioning

confidence: 62%

Severe enteritis in dogs associated with single and mixed infections

et al. 2024

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Infectious enteritis is highly prevalent among dogs worldwide and, in some cases, it can be fatal. This study describes the clinical and laboratorial findings of single and mixed infections associated with severe enteritis in 76 dogs from Southern Brazil. Intestinal segments and/or fecal samples were subjected to histopathology and molecular detection of DNA viruses, bacteria and protozoa. Severe intestinal lesions were observed in most cases. Single infections were detected in 52.6% of cases, double (36.8%) and triple (10.5%) infections were also identified. Carnivore protoparvovirus 2 (CPV-2) was the most frequent agent in single infections (36.8%). Coinfection by CPV-2 and Giardia spp. was the most common in dual infections (19.7%), followed by CPV-2 and Cryptosporidium spp. (10.5%). The most frequent triple infection was CPV-2, Giardia sp. and Cryptosporidium spp. (6.6%). Our results shown that single and mixed infections are associated with severe enteritis in dogs in southern Brazil, mainly involving CPV-2 and Giardia sp.

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Proposed New Strain of Canine Kobuvirus from Fecal Samples of Brazilian Domestic Dogs

Cited by 5 publications

References 14 publications

A Comprehensive Review on Human Aichi Virus

A Comprehensive Review on Human Aichi Virus

Detection of canine kobuvirus RNA in diarrheic fecal samples of dogs with parvoviruses

Severe enteritis in dogs associated with single and mixed infections

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