Proposed novel nomenclature of vulvar smooth muscle tumors; a case of Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) of the vulva

Viau, Mathieu; Plante, Marie; Renaud, Marie Claude; Grondin, Katherine; Morin, Chantale

doi:10.1016/j.gore.2017.01.006

Cited by 11 publications

(13 citation statements)

References 9 publications

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“…Smooth muscle tumors that do not fit into these categories are diagnosed as STUMP (2). Most STUMPs are of gynecological origin (especially uterine origin but also extrauterine origin) (3, 4) but scientific literature described rare cases of uroandrological origin. Hsieh et al (5) described, for the first time, a peri-urethral STUMP in a young woman while Zukerman et al (6) reported a rare “atypical” case of bladder STUMP.…”

Section: Discussionmentioning

confidence: 99%

Peri-prostatovesicular smooth muscle tumors of undetermined malignant potential: a case report

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Peri-prostatovesicular smooth muscle tumors of undetermined malignant potential: a case report

et al. 2017

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“…In addition, tumor necrosis should raise suspicion for the diagnosis of STUMP. 27 Epidemiology and clinical presentation: Clinical experience is too limited.…”

Section: Mesenchymal Tumors Of the Lower Genital Tractmentioning

confidence: 99%

“…Prognosis and outcome: STUMP is categorized as an intermediate smooth muscle tumor and is reported to be associated with a 7%-27% recurrence rate. 27,29 LEIOMYOSARCOMA OF THE LOWER GENITAL TRACT. Definition: Vulvar leiomyosarcomas account for merely 1% of all primary malignancies of the vulva, yet they represent the most common sarcoma of the vulva.…”

Section: Mesenchymal Tumors Of the Lower Genital Tractmentioning

confidence: 99%

“…The presence of at least 3 of the following histologic features, including infiltrating margins, >5 mitotic figures per 10 HPF, size >5 cm, and moderate to marked cytologic atypia, is associated with a poor prognosis of vulvar leiomyosarcoma (see Figure 1). 27,30 Epidemiology and clinical presentation: The mean age at incidence is between 35 and 50 years. The tumor arises mainly in the labium majus and the Bartholin gland area.…”

Section: Mesenchymal Tumors Of the Lower Genital Tractmentioning

confidence: 99%

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Nonsquamous Lesions of the Vulvar Skin and Subcutaneous Tissue: A Review (Part 2)

Rastegar

Aisner

Heller

2022

J Low Genit Tract Dis

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The aim of this second article was to complete part 1 review of nonsquamous lesions of the vulvar skin and subcutaneous tissue (Journal of Lower Genital Tract Disease, 2021), clinically and pathologically, based on the fifth edition of the World Health Organization tumor classification. Materials and Methods: A database search of PubMed and GoogleScholar was performed between 1970 and 2021, using the search terms "vulva," "lower genital tract," and "non-squamous lesions." The search was limited to "human gynecological pathology." Full article texts were reviewed, and reference lists were screened for additional articles. We excluded abstracts and articles written in the non-English language.Results: An initial list of 400 articles was identified. Thirty-seven articles discussed clinicopathological features of nonsquamous lesions of the vulvar skin and subcutaneous tissue.Conclusions: Clinicopathological features of nonsquamous lesions of the vulvar skin and subcutaneous tissue as categorized by the updated World Health Organization classification are presented.

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“…In contrast, smooth muscle neoplasms of the vulva are rather uncommon and represent a challenge for diagnosis and treatment. Three categories of vulvar smooth muscle tumors have been described: leiomyomas, atypical leiomyomas, and leiomyosarcomas (1,2).…”

Section: Introductionmentioning

confidence: 99%

Challenges in Management of Bartholin gland Leiomyoma: A Case Report

Vinturache

Ismail

Damato

et al. 2020

Preprint

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Abstract Background: Leiomyomas are uncommon vulvar neoplasms often misdiagnosed as other Bartholin gland pathology. Due to their rarity and the absence of guidelines, their diagnosis and management remain challenging, largely based on expert opinion and evidence from case reports. Case Presentation: This case report describes a 44-year-old woman presenting with accelerating growth of a vulvar mass. Based on clinical signs and symptoms, the initial diagnosis was Bartholin cyst. Surgical excision was provided for symptom control and aesthetic reasons. The histopathologic diagnosis was vulvar leiomyoma. The postoperative recovery was complicated by secondary haematoma and dehiscence of the surgical site. There was no recurrence at two years follow up. Therefore, we discuss the dilemma posed by physical examination of a vulvar mass, the challenges of the management, and report on secondary morbidity and long-term follow up, aspects of care for patients with vulvar pathology not commonly addressed in the literature. Conclusions: Bartholin gland neoplasms are rare tumors, commonly misdiagnosed as Bartholin’s cysts. Excision is the treatment of choice. Short time follow up allows prompt management of potential postoperative complications. Continuing long term follow up is recommended due to recurrence risk.

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Proposed novel nomenclature of vulvar smooth muscle tumors; a case of Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) of the vulva

Cited by 11 publications

References 9 publications

Peri-prostatovesicular smooth muscle tumors of undetermined malignant potential: a case report

Peri-prostatovesicular smooth muscle tumors of undetermined malignant potential: a case report

Nonsquamous Lesions of the Vulvar Skin and Subcutaneous Tissue: A Review (Part 2)

Challenges in Management of Bartholin gland Leiomyoma: A Case Report

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