Propoxylation of fatty amines: Switching from batch to flow

Abstract

The ethoxylation and propoxylation of fatty amines are important industrial reactions commonly performed in de-intensified semi-batch reactors. The present study aims to intensify these reactions by transferring the process to continuous processing. Therefore, the propoxylation of octylamine, as model system, was performed in a batch reactor and in a micro tubular reactor. The micro tubular reactor operated with a single liquid phase at 15 bar pressure.The batch study found valuable kinetic and solubility information in the temperature range of 120 C-160 C. Moreover, a switch-flow method in the micro tubular reactor combined with inline FTIR gave a more detailed understanding of the reaction kinetics. In the micro tubular reactor, all PO was added in the feed according to stoichiometry, which led to a process intensification factor of 3.7 compared to fed-batch gas phase addition at maximum 2 bar.

Automated multi-objective reaction optimisation: which algorithm should I use?

“…Ideal plug flow could be assumed as characterisation via residence time distribution experiments found Bodenstein numbers to be above 100 (ESI † section 3.3). 38 Additionally, a time equivalent of 1.5 reactor volumes was allowed to elapse before sampling. 39 Flow rates, reaction temperature and sampling were monitored by the MATLAB interface, which used the calibrated mass spectrum peak areas for analysis, with either the TSEMO or EIM-EGO algorithm to calculate the next reaction setting.…”

Migration of Dihydroxy Alkylamines and Their Possible Impurities from Packaging into Foods and Food Simulants: Analysis and Safety Evaluation

“…Generally, the preferred option is the combination of both antistatic agents that allows immediate and long-term antistatic protection due to the synergistic effect between the two classes of compounds [ 7 ]. In particular, ethoxylated fatty amines are extensively used as non-ionic antistatic agents [ 8 ]. Tallow is the traditional raw material used to produce fatty amines [ 9 ].…”

Special issue covering the Second International Process Intensification Conference (IPIC2)

“…Operating the oscillatory flow reactor in recirculation mode enables high solid processing and thus an avenue to further increase the efficiency of the process. To support the transition from batch to continuous manufacturing, van der Schaaf et al 3 report the propoxylation of octylamine in a batch reactor and in a microchannel reactor, resulting in a process intensification factor of 3.7 for continuous manufacturing. In terms of energy activation via light, Van Gerven et al 4,5 discuss the modeling and experimental validation of the novel concept of coaxial illumination for photochemical reactions.…”