2008
DOI: 10.1056/nejmc0708819
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Propranolol for Severe Hemangiomas of Infancy

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Cited by 2,054 publications
(1,578 citation statements)
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“…[2][3][4][5][6] However, these therapies have multiple side effects, some of which are serious. [7][8][9] In a recent case series, 10 propranolol was used to treat the obstructive hypertrophic myocardiopathy caused by corticosteroid therapy for an infantile hemangioma. Unexpectedly, the propranolol caused regression of the infantile hemangioma as well.…”
mentioning
confidence: 99%
“…[2][3][4][5][6] However, these therapies have multiple side effects, some of which are serious. [7][8][9] In a recent case series, 10 propranolol was used to treat the obstructive hypertrophic myocardiopathy caused by corticosteroid therapy for an infantile hemangioma. Unexpectedly, the propranolol caused regression of the infantile hemangioma as well.…”
mentioning
confidence: 99%
“…The side effects of chemotherapy are well known and radiotherapy carries the risk of inducing new tumour. Propranolol, a known non-selective beta-blocker, has been reported to induce regression in haemangiomas in newborns [17,18]. Sclerotherapy is the most common intervention in many centers around the world.…”
Section: Discussionmentioning
confidence: 99%
“…Врачи детской клиники «Бордо» во Франции назначили пропранолол пациенту с ИГ на лице, у которого предшествующее лечение предни-золоном осложнилось развитием обструктивной ги-пертрофической кардиомиопатии. Уже на следую-щий день после приема пропранолола ИГ стала светлее и мягче, а через несколько месяцев терапии препаратом на коже наблюдались только остаточ-ные явления в виде телеангиэктазий [13]. На сегод-няшний день препарат активно применяется как средство первого выбора при лечении сложных ИГ, в том числе у недоношенных и маловесных ново-рожденных [13,14].…”
Section: к хирургическим методам лечения иг относятсяunclassified