Propriospinal Negative Myoclonus

Okuma, Yasuyuki; Fujishima, Kenji; Machida, Yutaka; Inagaki, Naoko; Sugita, Yurina; Mizuno, Yoshikuni

doi:10.1159/000050773

Cited by 8 publications

(7 citation statements)

References 9 publications

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“…The most commonly reported effective treatment was based on clonazepam or other benzodiazepines. 2,21,22 This sometimes resulted in a mild to moderate improvement, while rare patients (1/9 in our series) had a major improvement. 3 Valproate was also reported to be helpful in isolated patients.…”

Section: Resultsmentioning

confidence: 64%

Propriospinal myoclonus revisited

Roze

Bounolleau²,

Ducreux³

et al. 2009

Neurology

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The clinico-physiologic spectrum of propriospinal myoclonus (PSM) is homogenous. Involvement of the abdominal wall muscles, worsening in the lying position, premonitory sensation, and wake-sleep transition phase worsening are helpful clinical clues. Diffusion tensor imaging with fiber tracking appears more sensitive than conventional MRI for detecting associated microstructural abnormalities of the spinal cord. Symptomatic treatment of PSM is not straightforward, and clonazepam is reported to be the most effective drug. Zonisamide may be an interesting option.

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Section: Resultsmentioning

confidence: 64%

Propriospinal myoclonus revisited

Roze

Bounolleau²,

Ducreux³

et al. 2009

Neurology

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“…The previously reported polymyographic patterns of PSM are summarized in Table 1 1–14. The duration of EMG activities in the recorded muscles was variable between the patients, as well as within each patient, and ranged from 20 milliseconds to 4 seconds.…”

Section: Discussionmentioning

confidence: 97%

“…The term “propriospinal” has been applied based primarily on the slow intraspinal propagation velocity of myoclonic activity as compared to the conduction velocity of the myoclonus of supraspinal origin in the corticospinal pathways 15. In most studies, the intraspinal propagation velocity was measured by dividing the length of the rostral and caudal spinal segments by the latency between the rostral and caudal muscles involved 1, 2, 4, 6–11, 14. In some studies, peripheral efferent time to the tested muscles was also measured by magnetically stimulating the nerve roots 1, 4, 10.…”

Section: Discussionmentioning

confidence: 99%

Electromyography patterns of propriospinal myoclonus can be mimicked voluntarily

Kang

Sohn

2006

Mov Disord.

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In order to investigate the clinical impact of polymyographic evaluation on the diagnosis of propriospinal myoclonus (PSM), we performed electromyography recordings of various truncal muscles in eight healthy volunteers while they mimicked PSM symptoms. Before the experiment, each volunteer learned how to mimic PSM by watching a videotape that showed typical PSM characteristics, i.e., brief symmetric flexion of the trunk. The recorded polymyographic patterns of all volunteers were quite compatible with those found in the previous reports. The present study demonstrates that previously known polymyographic patterns of PSM can be voluntarily mimicked. Additional studies, such as jerk-locked cortical potential, are required to confirm the diagnosis of true PSM.

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“…4 There are patients with propriospinal myoclonus who had trouble standing due to drop attacks. 14,20 Here, we report a severe and uncommon case of propriospinal myoclonus that appeared after vertebral trauma at age 7 months.…”

Section: Introductionmentioning

confidence: 93%

Propriospinal Myoclonus in a Child

et al. 2010

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A 6-year-old girl was experiencing repetitive involuntary and massive jerks immediately involving limbs and trunk. The first motor events appeared approximately at 1 year old and only 5 months after a back trauma. Myoclonus became progressively more frequent and more violent, causing episodes of falls. Neurological examination showed jerks characterized by upper limb abduction, lower limb abduction, and head-body hyperextension. Apart from these motor events, the neurological examination was normal. The results of vitamin B(12) and folate, antinuclear antibody, anti-DNA, anti-Tiroglobulin, anti-thyroid peroxidase antibody, lupus anticoagulant, anti-cardiolipin antibody, rheumatoid factor, and C3 and C4 were unexceptional. Electroencephalography and brain and spinal magnetic resonance imaging were unremarkable. Electromyographic records with surface electrodes showed that duration of myoclonic jerks was ranging from 100 to 300 ms. We thought she had propriospinal myoclonus because of presence of the spreading through the shoulder, upper limbs, and lower limbs in addition to thoracolumbar paraspinal muscles.

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Propriospinal Negative Myoclonus

Cited by 8 publications

References 9 publications

Propriospinal myoclonus revisited

Propriospinal myoclonus revisited

Electromyography patterns of propriospinal myoclonus can be mimicked voluntarily

Propriospinal Myoclonus in a Child

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