Proptose ocular como manifestação clínica de tumores malignos extra-orbitários: estudo pela tomografia computadorizada

Baptista, Ana Célia; Marchiori, Edson; Boasquevisque, Edson; Cabral, Carlos Eduardo Lassance

doi:10.1590/s0100-39842003000200006

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…A distance of 10 mm or less indicates exophthalmos ( 9 ). The level of proptosis is indicated by grades: grade 1 when more than two-thirds of the anteroposterior diameter of the eyeball is projected to the front of the line, grade 2 when the posterior pole of the globe border the line, and grade 3 when the entire eyeball is projected in front of this line ( 17 ).…”

Section: Introductionmentioning

confidence: 99%

Computed tomography and magnetic resonance imaging approaches to Graves’ ophthalmopathy: a narrative review

Luccas,

Riguetto,

Alves

et al. 2024

Front. Endocrinol.

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Graves’ ophthalmopathy (GO) affects up to 50% of patients with Graves’ disease (GD) ranging from mild ocular irritation to vision loss. The initial diagnosis is based on clinical findings and laboratory tests. Orbital imaging, such as magnetic resonance imaging (MRI) and computed tomography (CT), is an important tool to assess orbital changes, being also useful for understanding disease progression and surgical planning. In this narrative review, we included 92 studies published from 1979 to 2020 that used either MRI and/or CT to diagnose and investigate GO, proposing new methods and techniques. Most of the methods used still need to be corroborated and validated, and, despite the different methods and approaches for thyroid eye disease (TED) evaluation, there is still a lack of standardization of measurements and outcome reports; therefore, additional studies should be performed to include these methods in clinical practice, facilitating the diagnosis and approach for the treatment of TED.

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Section: Introductionmentioning

confidence: 99%

Computed tomography and magnetic resonance imaging approaches to Graves’ ophthalmopathy: a narrative review

Luccas,

Riguetto,

Alves

et al. 2024

Front. Endocrinol.

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Aspectos epidemiológicos, fatores de risco e achados clinicopatológicos do melanoma em cães no Sertão, Nordeste do Brasil

Lopes de Lima,

Platini Ferreira de Souto,

Norberto de Oliveira

et al. 2022

Acta Scientiae Vet.

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Background: Melanoma is a malignant neoplasm that arises from melanocytes and malanoblasts. It is also more frequently reported in dogs than in other species. They may arise from melanocytes in the skin, on the surfaces of the mucous membranes, and eyes. The aim of this study was to describe the epidemiological aspects, risk factors and clinicopathological findings of melanoma in dogs in the backlands, northeastern Brazil. Materials, Methods & Results: Biopsies and necropsies performed on dogs at the Animal Pathology Laboratory of the Federal University of Campina Grande during the period from 2000 to 2021 were reviewed. Of the 4717 records found, 1158 (24.5%) were diagnosed with neoplasms, of which 48 (4.14%) cases were of melanoma. Of this total, 28 (58.3%) dogs were elderly, 19 (39.6%) were adults, and one (2.1%) was young. Mixed breed animals were the most affected (42.6%), followed by the pinscher breed (19.1%). The neoplasms were in the skin, oral cavity, and eyeball. In nine (18.75%) cases, metastases were identified, eight in lymph nodes and one in the lung. The lesions were located mainly on the skin and were characterized by a nodular and blackened growth pattern. Discussion: The diagnosis of melanoma was established based on epidemiological, clinical, anatomopathological, and immunohistochemical findings. Gender is not a predisposing factor, and although there was no statistically significant relationship, males were more affected. Senescence is a conditioning risk factor. Elderly animals were more affected (p < 0.0001) than adult ones, with OR = 4.38; and young ones (p = 0.0051), with OR = 12.65. Some breeds, especially those with marked skin pigmentation, were more affected, however the most affected ones in this survey were pinscher and poodle. Cutaneous melanoma accounted for almost 72% of cases, contesting recent studies where oral cavity melanoma was more frequent. Therefore, it is believed that the climatic conditions of the Sertão sub-region, in Northeastern Brazil, associated with the individual characteristics of the dogs, are involved in the development of these neoplasms, since the climate is predominantly dry, with high temperatures throughout the year, with maximums that can reach 40ºC, favoring the exposure to high incidence of ultraviolet radiation. Keywords: Dog disease, dermatopathy, neoplasm, melanocytes.

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Proptose ocular como manifestação clínica de tumores malignos extra-orbitários: estudo pela tomografia computadorizada

Cited by 2 publications

References 28 publications

Computed tomography and magnetic resonance imaging approaches to Graves’ ophthalmopathy: a narrative review

Computed tomography and magnetic resonance imaging approaches to Graves’ ophthalmopathy: a narrative review

Aspectos epidemiológicos, fatores de risco e achados clinicopatológicos do melanoma em cães no Sertão, Nordeste do Brasil

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