Prospective and Randomized Study to Evaluate the Clinical Impact of Cap Assisted Colonoscopy (CAC)

Frieling, Thomas; Neuhaus, F.; Kuhlbusch-Zicklam, R.; Heise, Jeffrey A.; Kreysel, C.; Hülsdonk, A.; Blank, Marion; Czypull, M.

doi:10.1055/s-0033-1335637

Cited by 22 publications

(44 citation statements)

References 17 publications

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“…In recent years, performance of CAC has increasingly become popular among gastroenterologists. In a prospective and randomized study to evaluate the clinical impact of cap-assisted colonoscopy, Frieling et al [66] found a significant higher cecal intubation time when using a transparent cap. However, there are contradictory results for improving the ADR.…”

Section: Technical Aspectsmentioning

confidence: 99%

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Floer

Meister²

2016

Digestion

238

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Background: The presence of colorectal adenomas is considered a major risk factor for colorectal cancer development. The implementation of screening colonoscopy programs in the Western world has led to a substantial reduction of colorectal cancer death. Many efforts have been made to reduce the adenoma miss rates by the application of new endoscopic devices and techniques for better adenoma visualization. Summary: This special review gives the readership an overview of current endoscopic innovations that can aid in the increase of the adenoma detection rate (ADR) during colonoscopy. These innovations include the use of devices like EndoCuff® and EndoRings® as well as new technical equipment like third-eye endoscope® and full-spectrum endoscopy (FUSE®). Key Message: Technical improvements and newly developed accessories are able to improve the ADR. However, additional costs and a willingness to invest into potentially expensive equipment might be necessary. Investigator-dependent skills remain the backbone in the ADR detection.

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Section: Technical Aspectsmentioning

confidence: 99%

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Floer

Meister²

2016

Digestion

238

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“…Three studies including 2 prospective RCTs [7,8] and 1 retrospective study [9] , all from Germany describing the EC were included for the review. Six prospective RCTs, 1 each from Germany [10] , Hong Kong [11] , Netherlands [12] , US [13] , South Korea [14] , Australia [15] and 1 retrospective study from Hong Kong [16] describing the CAC were included for the review. One multicenter (Netherlands, Israel and US) RCT describing ERC was also included [17] .…”

Section: Resultsmentioning

confidence: 99%

“…In the prospective studies, the study subjects were grouped into 2 arms based on the type of intervention: EC [7][8][9] or CAC [10][11][12][13][14][15] or ERC [17] versus standard colonoscopy (SC), regular colonoscopy (RC) or conventional colonoscopy (CC). The retrospective studies looked into the EC [9] and CAC [16] performed.…”

Section: Type Of Colonoscopy and Technical Aspectmentioning

confidence: 99%

“…2 a and b). Frieling et al [10] used conventional video Fujionon colonoscope for both CAC and CC. For the CAC, the colonoscope was attached with a conventional transparent mucosectomy cap of the Olympus D201 series [10] .…”

Section: Colonoscope and Its Accessoriesmentioning

confidence: 99%

“…Frieling et al [10] used conventional video Fujionon colonoscope for both CAC and CC. For the CAC, the colonoscope was attached with a conventional transparent mucosectomy cap of the Olympus D201 series [10] . Suction and insufflation of air through the endoscope was Lack of cecum intubation 2 subjects None IQR = Interquartile range; DNA = data not available; AC = ascending colon; HF = hepatic flexure; SF = splenic flexure; TC = transverse colon; DC = descending colon; GCS = Gloucester Comfort Scale; NS = not significant; IVF = intravenous fluids.…”

Section: Colonoscope and Its Accessoriesmentioning

confidence: 99%

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New Developments in Mechanical Enhancement of Colonoscopy: Cuffs, Caps and Rings

Jain

Sandhu

Singhal³

2016

Digestion

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Background: Colorectal cancer (CRC) is a common cause of cancer-related deaths. Early detection of precursor lesions in the adenoma-carcinoma sequence via colonoscopy can decrease mortality from CRC. Summary: In this review article, we have summarized retrospective studies, prospective single center, multicenter studies and randomized controlled trials describing the efficacy of endocuff colonoscopy (EC), cap-assisted colonoscopy (CAC) and endorings colonoscopy (ERC). Indications, techniques, outcomes, limitations and complications reported are discussed. Key Message: Use of colonoscope with cap, cuff or rings attached to its distal tip has been shown to increase the polyp detection rate and adenoma detection rate, predominantly for the small polyps (<1 cm) and proximal colon location. Evidence is uniform for EC and ERC but not for CAC. Benefits of shorter cecum intubation time, improved cecum intubation rates and decreased pain scores during colonoscopy done with assistance of cuff or cap has potential to decrease the number of incomplete colonoscopy and increase overall patient satisfaction, thus improving follow-up. In the absence of any additional adverse events, EC, CAC and ERC have potential to enhance the benefits of colonoscopy.

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Colonoscopy for Colorectal Cancer Screening: Current Challenges and Future Directions

Morales

Magulick

Womeldorph

et al. 2014

Curr Colorectal Cancer Rep

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Prospective and Randomized Study to Evaluate the Clinical Impact of Cap Assisted Colonoscopy (CAC)

Abstract: CAC was without clinical impact on polyp detection rate or performance of colonoscopy.

Cited by 22 publications

References 17 publications

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

New Developments in Mechanical Enhancement of Colonoscopy: Cuffs, Caps and Rings

Colonoscopy for Colorectal Cancer Screening: Current Challenges and Future Directions

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