2007
DOI: 10.1177/0003319707305685
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Prospective Assessment of Lower-Extremity Peripheral Arterial Disease in Diabetic Patients Using a Novel Automated Optical Device

Abstract: A new optical device based on the photoplethysmograph (PPG) method and an innovative algorithm for the assessment of lower-extremity peripheral arterial disease was investigated prospectively in patients with type II diabetes. This new functional PPG (fPPG) technique uses a cuffless functional test to assess diabetic peripheral arterial disease without operator dependency and the incompressible arteries, issues associated with ankle brachial pressure index (ABPI) measurement. Diabetic patients (n = 24; 47 legs… Show more

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Cited by 38 publications
(41 citation statements)
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“…32 one used ABI > 1.3 for PAD; 33 one included patients with stenosis > 70% in leg arteries; 34 10 articles did not use an appropriate reference standard for PAD; [35][36][37][38][39][40][41][42][43][44] one paper had a sample size of only 39 patients; 45 and three were review articles. [46][47][48] Figure 1 shows the study selection process.…”
Section: Resultsmentioning
confidence: 99%
“…32 one used ABI > 1.3 for PAD; 33 one included patients with stenosis > 70% in leg arteries; 34 10 articles did not use an appropriate reference standard for PAD; [35][36][37][38][39][40][41][42][43][44] one paper had a sample size of only 39 patients; 45 and three were review articles. [46][47][48] Figure 1 shows the study selection process.…”
Section: Resultsmentioning
confidence: 99%
“…Importantly, these early arteriolar lesions occur prior to clinical manifestations of DM, and are potentially reversible at this stage. When disease progresses, pathological changes in arterioles become irreversible due to persistent metabolic disorders, and result in serious complications such as acral ischemic gangrene [3,4], diabetic nephropathy [1,5], etc.…”
Section: Introductionmentioning
confidence: 99%
“…However, the application of this index should be carefully considered in patients with arterial calcification, such as those with the long-term morbidities of diabetes mellitus and with end-stage kidney disease on maintenance dialysis [30,31]. It is possible that the ABI might normalize from an originally low level, because calcification is more remarkable in the arteries close to the heart than in those in the ankles.…”
Section: Discussionmentioning
confidence: 99%