Prospective Case Study on Characterization of Colorectal Adenomas Comparing AFI with NBI

Abstract

Aim. Compare the characterization ability of AFI and NBI for colorectal adenomas. Methods. We prospectively enrolled 58 patients with 89 colorectal adenomas detected by white light colonoscopy. Such lesions were subsequently observed with both AFI and NBI and then treated by endoscopic resection. With respect to the 89 lesions, 3 experienced endoscopists retrospectively evaluated the visualization quality of the AFI and NBI images in a blind manner using a three-tier scale based on excellent, fair, and poor criteria. Results. There were 54, 31, and 4 lesions considered as excellent, fair, and poor visualization, respectively, using AFI in comparison to 53, 19, and 17 lesions, respectively, with NBI. The percentage of excellent and fair visualization lesions was 95.5% with AFI and 80.9% with NBI (P < .01). Conclusion. This study indicated that AFI may be more effective for the characterization of colorectal adenomas because of better visualization of such lesions compared to NBI.

Visualization of Laterally Spreading Colorectal Tumors by Using Image-Enhanced Endoscopy

“…The utility of AFI for the detection of colorectal tumors still remains controversial, with studies reporting mixed results [7–9, 15, 19]. In this study, 2 LST-NG lesions were determined to be well visualized by 4 endoscopists (Figures 3 and 4.).…”

Comparison of diagnostic efficacy between AFI, NBI, and AFI combined with NBI for colonic cancers: A meta-analysis

“…From these studies, 210 were excluded as duplicates and 723 were excluded after reviewing the titles and abstracts. After a review of the full-texts, the reasons for the final study exclusion were as follows: (1) insufficient data were reported to calculate TP, FP, TN, and FN (N = 2);[1213] (2) different evaluation methods for diagnostic efficacy were used (N = 2);[114] (3) suspicious data duplications appeared in similar studies (N = 3). [151617] Finally, 8 studies were included in our analysis, comprising a total of 660 patients and 1426 lesions.…”

“…These results seem to be inconsistent with the study from Suzuki et al ., which concluded that AFI might be more effective for the characterization of colorectal adenomas than NBI. [1] The main reason for this difference may be that a unique research method was used by Suzuki et al ., which compared the visualization quality between the two modalities. The inclusion of patients may also play a role in this situation.…”

“…However, some specific lesions may be missed (such as small or flat adenomas) or difficult to detect (such as depressed-type colorectal tumors and nongranular-type laterally spreading tumors) during conventional colonoscopy examinations;[1] Removal of non-neoplastic polyps with standard white light colonoscopy (WLC) occurs occasionally, and such inappropriate polyp resection may lead to unnecessary risks of perforation or bleeding. [2] Advanced endoscopic imaging technologies are needed to assist endoscopists in dealing with these problems.…”

What is the accuracy of autofluorescence imaging in identifying non‐polypoid colorectal neoplastic lesions when reviewed by trainees? A pilot study

“…This means that the identification of smaller neoplasms when reviewed by trainees was similar between the two systems. The AFI system has been shown to provide significantly better visualization and differentiation of non‐polypoid colorectal neoplasms than that provided by WL colonoscopy, which is an advantage of the AFI system . Any type of IEE, including AFI and NBI, has its own special characteristics.…”