Prospective Evaluation of a Negative Pressure Dressing System in the Management of the Fibula Free Flap Donor Site

Abstract

Our findings would, at best, suggest that NPD may decrease the rate of return to the operating theater for donor site problems. The fibula donor site healing remains problematic, and our results suggest that routine use of the NPD system in the management of the fibula free flap donor site is not justified from a health economic perspective.

Programmable Mechanobioreactor for Exploration of the Effects of Periodic Vibratory Stimulus on Mesenchymal Stem Cell Differentiation

“…1,2 These defects are generally treated with autologous grafts that require a secondary surgical site and can be associated with significant donor-site morbidity. 3,4 The capacity of tissue engineering (TE) to provide solutions to these challenges is significant. Mesenchymal stem cells (MSCs) for TE are widely available from multiple sources and have immense potential to treat these bone and cartilage defects.…”

Tailored approach to oromandibular reconstruction in patients with compromised lower limb vessels

“…Although precise donor site morbidity was not measured for this study, no catastrophic complications (eg, ischemic foot) occurred. The fibula donor‐site complication rate for this cohort has previously been published …”

“…The fibula donor-site complication rate for this cohort has previously been published. 22 The possibility of congenital anomalies, traumatic deformity, or peripheral vascular disease affecting the tibioperoneal trunk, means that preoperative vascular assessment of the lower limb is essential before fibula harvest and, in our unit, all patients being considered for fibula flap harvest undergo MRA examination of their lower limbs. The proportion of patients in this study in which the fibula was excluded because of unfavorable preoperative MRA (26%) is higher than expected.…”

Comparison of negative pressure wound therapy and conventional dressing methods for fibula free flap donor site management in patients with head and neck cancer

“…The only published study comparing conventional dressings and negative pressure wound therapy on fibula free flap donor sites failed to demonstrate any significant difference for donor site total healing time according to the type of dressing . Negative pressure wound therapy was applied for 5 days and bolster dressings were applied for 10 days.…”

“…5,10,12,14 The only published study comparing conventional dressings and negative pressure wound therapy on fibula free flap donor sites failed to demonstrate any significant difference for donor site total healing time according to the type of dressing. 15 Negative pressure wound therapy was applied for 5 days and bolster dressings were applied for 10 days. The negative pressure wound therapy group had a higher graft acceptance rate and required fewer home dressing changes, but presented a higher infection rate.…”