Prospective evaluation of an anti-cancer drugs management programme in a dedicated oral therapy center (DICTO programme)

Abstract

Oral therapies have highly modified cancer patient management and changed hospital practises. We introduce a specific Oral Therapy Centre and retrospectively review information prospectively recorded by co-ordination nurses (CNs) (the DICTO programme). We describe the roles played by CNs in the management of oral cancer therapies at Limoges Dupuytren Hospital between May 2015 and June 2018. All cancers, irrespective of stage or whether oral general chemotherapy or targeted therapy was prescribed, are included. We followed up 287 patients of median age 67 years (range 26–89 years). Of these, 76% had metastases and 44% were on first-line therapy. The vast majority (88%) of their first CN contacts occurred just after physician consultation and lasted an average of 60 min. As part of follow-up, the CNs made 2719 calls (average 10 min) to patients to educate them and to verify compliance and drug tolerance. They also received 833 calls from patients (70%) or their relatives or health professionals (30%) seeking advice on management of side effects. In addition to the initial appointments, 1069 non-scheduled follow-up visits were made to assess side effects (49.2%). The CNs devoted 5 h to each patient over 3 months of treatment (i.e. 25 min/day) and, also organised scheduled hospitalisations in the department of oncology for 51% of patients. We show the interest and real-life work in a specific oral therapy centre within oncology department with the role of CNs to facilitate the global health care of the patients. Electronic supplementary material The online version of this article (10.1007/s12032-020-01393-7) contains supplementary material, which is available to authorized users.

A community-based ANP-led integrated oncology care model for adults receiving oral anticancer medication-protocol for a pilot study

“…High risk patients to have a phone call made to them days 8 and 10 (Deluche et al, 2020). All patients to have a phone call made to them days 15 & 30 (Deluche et al, 2020). Contact or visits are beneficial especially in the 1st 2 cycles to improve treatment and symptoms experience (Vidall, 2010 1 ; Oakley et al, 2014; Wong et al, 2016).…”

“…Clinical SACT services should provide a 24-hour telephone advice service for patients prescribed oral therapies, with appropriately trained nursing, medical or pharmacy staff handling queries (UKONS, 2010; Deluche et al, 2020).…”