Prospective Evaluation of Concurrent Meniscus Transplantation and Articular Cartilage Repair

Rue, John-Paul; Yanke, Adam B.; Busam, Matthew; McNickle, Allison G.; Cole, Brian J.

doi:10.1177/0363546508317122

Cited by 154 publications

(128 citation statements)

References 43 publications

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“…The results of patients who undergo combined cartilage repair with meniscal allograft transplantation are equivalent or superior to those reported for cartilage repair as an isolated procedure [25,65]. Rue et al [65] reported a series of 30 patients with combined meniscal allograft transplantation procedures and cartilage restoration procedures. Using various standardized outcome surveys including the Lysholm, International Knee Documentation Committee, and SF-12 scales, these authors demonstrated 76% of patients were completely or mostly satisfied with their surgical results and 90% would have surgery again.…”

Section: Patient Selectionmentioning

confidence: 96%

“…Even partial meniscectomy is associated with increases in tibiofemoral contact forces [42]. The results of patients who undergo combined cartilage repair with meniscal allograft transplantation are equivalent or superior to those reported for cartilage repair as an isolated procedure [25,65]. Rue et al [65] reported a series of 30 patients with combined meniscal allograft transplantation procedures and cartilage restoration procedures.…”

Section: Patient Selectionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Cartilage Restoration: Evolution and Overview

Farr

Cole

Dhawan

et al. 2011

Clinical Orthopaedics &Amp; Related Research

218

166

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Background Clinical cartilage restoration is evolving, with established and emerging technologies. Randomized, prospective studies with adequate power comparing the myriad of surgical techniques used to treat chondral injuries are still lacking and it remains a challenge for the surgeon treating patients to make evidence-based decisions. Questions/purposes We reviewed the history of the major cartilage repair/restorative procedures, indications for currently available repair/restorative procedures, and postoperative management. Methods We performed searches using MEDLINE and cartilage-specific key words to identify all Englishlanguage literature. Articles were selected based on their contributions to our current understanding of the basic science and clinical treatment of articular cartilage lesions or historical importance. We then selected 77 articles, two of which are articles of historical importance. Results Current cartilage restorative techniques include débridement, microfracture, osteochondral fragment repair, osteochondral allograft, osteochondral autograft, and autologous chondrocyte transplantation. Pending techniques include two-staged cell-based therapies integrated into a variety of scaffolds, single-stage cell-based therapy, and augmentation of marrow stimulation, each with suggested indications including lesion size, location, and activity demands of the patient. The literature demonstrates variable improvements in pain and function contingent upon multiple variables including indications and application. Conclusions For the patient with symptomatic chondral injury, numerous techniques are available to the surgeon to relieve pain and improve function. Until rigorous clinical trials (prospective, adequately powered, randomized control) are available, treatment decisions should be guided by expert extrapolation of the available literature based in historically sound principles.

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Section: Patient Selectionmentioning

confidence: 96%

Section: Patient Selectionmentioning

confidence: 99%

Clinical Cartilage Restoration: Evolution and Overview

Farr

Cole

Dhawan

et al. 2011

Clinical Orthopaedics &Amp; Related Research

218

166

View full text Add to dashboard Cite

show abstract

“…Most failures (85%) of combined surgery were due to failure of the MAT. Rue et al 200 performed simultaneous combined MAT and cartilage restoration procedures in 31 patients with a symptomatic postmeniscectomy knee with a focal chondral defect. MAT offers a safe alternative for those patients.…”

Section: Results Of Meniscal Transplantsmentioning

confidence: 99%

Meniscus tear surgery and meniscus replacement

Vaquero

Forriol

2016

MLTJ

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SummaryObjective: the menisci are easily injured and difficult to repair. The aim of this study was to analyze the current state of meniscal surgery aimed at preserving morphology and conserving the biomechanics of the knee to prevent joint degeneration. Methodology: a search of the electronic medical literature database Medline was conducted, from http://www.ncbi.nlm.nih.gov/pubmed. The search was not limited by language. Candidate articles were identified by searching for those that included the keywords meniscus, surgery, suture, implant, allograft. The limits were included for clinical research and clinical trials. Basic research was not included. The studies selected were evaluated and classified in three different categories: basic science, reconstruction (suture and meniscectomy) and implants (scaffolds and allograft). Results: the consequences of meniscectomy performed at a young age can lead to a joint cartilage degeneration twenty years later. There are few surgical options for the repair of meniscal injuries in order both to preserve the meniscus and to ensure the long term survival of the knee joint, meniscectomy, repair, suturing the tear, or reconstruction, when a meniscal allograft or synthetic substitute is used to replace the meniscus, but the biomechanical properties of the native meniscus are not reproduced entirely by the scaffolds that exist today.Conclusion: therapies that successfully repair or replace the meniscus are therefore likely to prevent or delay osteoarthritis progression.

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“…El Attar et al, found a mean failure rate of 10.6% and mean complications rate of 21.3% per trial in their systematic review [7]. Failure has been reported to occur at a mean of 2-3 years [32], 5 years [33], and 11.8 years [17]. The failure rate for medial allograft is higher compared to the lateral allograft [29].…”

Section: Complicationsmentioning

confidence: 99%

“…In general, the results of MAT associated with anterior cruciate ligament reconstruction or cartilage repair/ restoration are not worst compared to isolated MAT [6][7][8]. MAT and associated cartilage procedures (autologous chondrocyte implantation, osteochondral allograft, osteochondral autograft or microfractures) essentially provide similar improvement in pain relief, KOOS score, IKDC score (subjective), Noyes score, Tegner score, and sports level compared to isolated MAT [15,32,34,69,70]. Only Lysholm and modified Cincinnati scores were lower in the combined compared to isolated MAT [71,72].…”

Section: Associated Proceduresmentioning

confidence: 99%

Meniscal Allograft Transplantation: Where are we Standing?

Monllau¹,

Alentorn-Geli²,

Pelfort³

et al. 2013

J Transplant Technol Res

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Meniscal allograft transplantation (MAT) is becoming a common procedure in Orthopedic departments worldwide. This procedure has demonstrated good and excellent results in terms of pain relief, improvement in clinical and functional outcomes, return to sports, and patient's satisfaction. However, MAT is not a universally accepted procedure due to its questionable chondroprotective effects and the relatively high rate of complications and/or reoperations. The present short review summarizes the principal indications, contraindications, outcomes, and complications. Also, it covers several controversial topics like graft preservation, graft sizing, graft fixation, results in MAT associated with concomitant procedures, and the role of MAT in the prevention of knee osteoarthritis.

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Prospective Evaluation of Concurrent Meniscus Transplantation and Articular Cartilage Repair

Cited by 154 publications

References 43 publications

Clinical Cartilage Restoration: Evolution and Overview

Clinical Cartilage Restoration: Evolution and Overview

Meniscus tear surgery and meniscus replacement

Meniscal Allograft Transplantation: Where are we Standing?

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