Prospective Evaluation of Patient Usage of Above and Below Threshold Waveforms With Traditional Spinal Cord Stimulation Devices

Owusu, Stephanie; Huynh, Alexander; Gruenthal, Eric; Prusik, Julia; Owusu-Sarpong, Stephane; Cherala, Rasan; Peng, Sophia; Pilitsis, Julie G.; McCallum, Sarah E.

doi:10.1111/ner.12633

Cited by 9 publications

(11 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In general, patients who chose a SP‐SCS program were mainly workers and active people and the SP‐SCS program was reported to be a good solution that did not cause any tingling during activities. However, the patient preferences were widely heterogeneous, half PB‐SCS preference, half SP‐SCS waveform, with also subgroups in it, and cannot be predicted a priori , an observation that has already been reported by other authors . There was no correlation reported among different waveform preference (PB‐SCS, burst, or 1 kHz rate) and SCS implant age or different education level.…”

Section: Discussionmentioning

confidence: 69%

“…The study reported here is unique; no similar studies have been performed with this design, although other studies using multimodal stimulation have already been published (10,13,14,17,18). According to the registry reported by (17), 40% of patients preferred PB-SCS stimulation (without the bias of previous experience of PB-SCS stimulation, as in our study) and the rest instead chose daily usage of multimodal options (burst, 1 kHz frequency, anodic intensification). Overall, 51.4% of patients use SP-SCS waveforms (sum of only burst and 1 kHz rate), as well as combinations of two programs (including PB-SCS stimulation) on the same day.…”

Section: Discussionmentioning

confidence: 98%

“…This consideration may be different in de novo patients, as reported in Refs. (14,17) and from our ongoing new study.…”

Section: Discussionmentioning

confidence: 99%

“…New modalities may potentially enlarge the SCS application and overall clinical outcomes, with personalized SCS therapy options (12). The success of these novel modalities have been reported (2,(13)(14)(15)(16)(17)(18), the exact mechanisms are still being elucidated, but some clues have been revealed (7,15,(18)(19)(20). Moreover, the patient specific profile perceptions contributes to the heterogeneity of the results (7,9,14).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Effects of Multiple Waveforms on Patient Preferences and Clinical Outcomes in Patients Treated With Spinal Cord Stimulation for Leg and/or Back Pain

Duse¹,

Reverberi²,

Dario

2019

Neuromodulation: Technology at the Neural Interface

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 98%

“…This consideration may be different in de novo patients, as reported in Refs. (14,17) and from our ongoing new study.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of Multiple Waveforms on Patient Preferences and Clinical Outcomes in Patients Treated With Spinal Cord Stimulation for Leg and/or Back Pain

Duse¹,

Reverberi²,

Dario

2019

Neuromodulation: Technology at the Neural Interface

View full text Add to dashboard Cite

“…The main criticism of higher frequency SCS is greater recharging requirements than with conventional SCS. However, it is not clear whether this is universally true and further evaluation is required 1,7 …”

Section: Case Scenariomentioning

confidence: 99%

Conventional versus High‐Frequency Neuromodulation in the Treatment of Low Back Pain Following Spine Surgery

Sclafani

Leong

Desai

et al. 2019

PM&R

View full text Add to dashboard Cite

A 54-year-old man presents with history of low back pain radiating to the right lateral leg as well as pain in the dorsum of the foot. He describes the symptoms as stabbing and burning. The symptoms began 5 years ago at which point he was treated with neuropathic medications, two rounds of epidural steroid injections, both transforaminal and interlaminar approaches, as well as physical therapy. Four years ago, the patient underwent an L4-S1 transforaminal lumbar interbody fusion for stenosis and neurogenic claudication. He did well for 3.5 years and reported 80% to 90% relief during that time. He now presents with recurrence of primarily low back pain (90%) with minimal right leg pain. Updated imaging reveals stable hardware and no evidence of adjacent segment disease. The spinal canal is patent and there is mild foraminal stenosis at L4-5 and L5-1. Both a caudal epidural steroid injection and sacroiliac joint injections were unsuccessful. Currently the patient is taking 50 mg morphine equivalent daily and gabapentin and baclofen. Electrodiagnostics demonstrate chronic mild right L5 radiculopathy. The patient has read about spinal cord stimulation online and is interested in learning more about this therapy modality. You first address his psychological profile through a formal evaluation and no red flags are noted that would preclude proceeding. Drs. Joseph Sclafani and Michael Leong will argue that conventional neurostimulation has a proven track record of success and this modality will offer this patient the best coverage of his pain. Drs. Mehul Desai, Neel Mehta, and Dawood Sayed will argue that new waveform high-frequency (HF) stimulation is more likely to provide this patient with pain relief and functional improvement.

show abstract

A prospective, multicenter, international study to explore the effect of three different amplitude settings in female subjects with urinary urge incontinence receiving interstim therapy

Ehlert¹,

Ridder

McCrery

et al. 2021

Neurourology and Urodynamics

View full text Add to dashboard Cite

The aim of this study is to evaluate the effect of sub-sensory amplitude settings of sacral neuromodulation therapy on overactive bladder symptoms in subjects with urinary urge incontinence. Methods: Subjects who qualified for a neurostimulator device implant were randomized to one of three amplitude settings (50% of sensory threshold [ST], 80% of ST, and ST). Subjects completed urinary voiding diaries (3-day), International consultation on incontinence modular questionnaire-overactive bladder symptoms quality of life questionnaire, and patient global impression of improvement (PGI-I) to assess change in voiding symptoms and quality of life (QoL) from baseline through 12 weeks. Results: Forty-eight subjects had a successful test stimulation, 46 were implanted with a neurostimulator device and 43 completed the 12-week followup visit. The change from baseline to 12 weeks is −3.0 urinary incontinence (UI) episodes/day (95% confidence interval [CI]: −4.4 to −1.7) for the 50% of sensory threshold group, −2.9 UI episodes/day (95% CI: −4.7 to −1.2) for 80% of sensory threshold group, and −3.6 UI episodes/day (95% CI: −5.2 to −1.9) for the sensory threshold group. In each randomized group, improvements were observed in health-related QoL, its subscales, and symptom interference. Subjects across all three randomization groups reported on the PGI-I that their bladder condition was better at 12 weeks compared to before they were treated with InterStim therapy. Conclusion: These findings provide insights into possible advancements in the postimplantation phase of therapy with potential for improved patient comfort and increased device longevity. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

show abstract

Prospective Evaluation of Patient Usage of Above and Below Threshold Waveforms With Traditional Spinal Cord Stimulation Devices

Cited by 9 publications

References 18 publications

Effects of Multiple Waveforms on Patient Preferences and Clinical Outcomes in Patients Treated With Spinal Cord Stimulation for Leg and/or Back Pain

Effects of Multiple Waveforms on Patient Preferences and Clinical Outcomes in Patients Treated With Spinal Cord Stimulation for Leg and/or Back Pain

Conventional versus High‐Frequency Neuromodulation in the Treatment of Low Back Pain Following Spine Surgery

A prospective, multicenter, international study to explore the effect of three different amplitude settings in female subjects with urinary urge incontinence receiving interstim therapy

Contact Info

Product

Resources

About