Prospective Evaluation of Post-implantation Inflammatory Response After EVAR for AAA: Influence on Patients' 30 Day Outcome

Abstract

A systematic inflammatory response is observed in a significant number of patients after EVAR. The type of endograft material seems to play a significant role in this inflammatory process. The intensity of inflammation, as assessed mainly by the post-operative hs-CRP values, correlates with the presence of a cardiovascular or any other adverse event during the first 30 days after the procedure.

The Impact of Stent Graft Material on the Inflammatory Response After EVAR

“…Among the 69 patients from the whole group, 24 were excluded, mainly due to the use of graft material outside a standard EVAR (n ¼ 12) or open procedures in the vascular access site (n ¼ 6). All excluded cases are listed in Table 1.…”

Endovascular Management of Abdominal Aortic Aneurysms: the Year in Review

“…An important finding regarding the systemic inflammatory response was that post-operative hs-CRP levels were highly associated with cardiovascular events in the 30-day post-operative period. Synthetic polyester, used as graft material (as opposed to PTFE), appears to produce a greater inflammatory response, and may be an independent predictor of post-implantation syndrome [66,67]. Further study needs to be done to determine whether these findings should influence choice of graft.…”

Comparative Effectiveness of a Regional Virtual Tumor Board vs. Standard Care for Patients with Hepatocellular Cancer in a Regional Health Network

“…Post-implantation syndrome (PIS) is an acute-phase inflammatory response that frequently occurs after EVAR with an estimated incidence of 34% [16]. PIS usually presents within 24 hours to 48 hours of stent graft implantation and manifests as a systemic inflammatory response syndrome.…”