Prospective Longitudinal Substance Use Patterns in Patients Preparing for Hepatitis C Treatment

North, Carol S.; Pollio, David E.; Sims, Omar T.; Jain, Mamta K.; Hong, Barry A.

doi:10.1080/15504263.2017.1380246

Cited by 9 publications

(3 citation statements)

References 27 publications

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“…The HCV Effects on Functioning Questionnaire assessed functioning in the past month with regard to employment, home management, social leisure, personal leisure, personal relationships, and sex life. Psychometric properties of the HCV Effects on Functioning Questionnaire were not pretested, but the modified questionnaire has been used elsewhere (North et al, 2017; North, Pollio, Sims, Hong, 2018).…”

Section: Methodsmentioning

confidence: 99%

“…Question items included but were not limited to turning to work or other activities such as sleeping or TV, family or friends for emotional or moral support, and religion/spirituality. Psychometric properties of the HCV Effects on Functioning Questionnaire were not pretested, but the modified questionnaire has been used elsewhere (North et al, 2017; North et al, 2018).…”

Section: Methodsmentioning

confidence: 99%

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Quality of Life, Functioning, and Coping in HCV Patients Continuing Versus Ceasing Alcohol Use

Sims

Pollio

et al. 2019

Health Promotion Practice

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The purpose of this study was to compare quality of life, functioning, and coping among hepatitis C virus (HCV) patients who continued versus ceased alcohol use in the past year. HCV patients ( n = 291) were recruited from three liver and infectious disease clinics. Student’s t test was used to compare HCV patients who were former and active users of alcohol. The majority of HCV patients were male, African American, and without a high school degree. Compared to former users of alcohol, active users of alcohol self-reported lower ratings on home life, personal leisure, and overall quality of life. In the area of functioning, active users of alcohol self-reported lower ratings on home life, close relationships, sex life, and overall functioning. The two groups did not differ on coping. Most HCV clinicians advise HCV patients to avoid alcohol completely because of its adverse biological effects on the liver. Despite this important advice by their HCV clinicians, most HCV patients continue to use alcohol. HCV clinicians can additionally consider advising these patients that continued alcohol use is associated with lower quality of life and functioning as further evidence to convince these patients to avoid alcohol or to participate in alcohol cessation treatment.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Quality of Life, Functioning, and Coping in HCV Patients Continuing Versus Ceasing Alcohol Use

Sims

Pollio

et al. 2019

Health Promotion Practice

Self Cite

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“…Comorbid social or health conditions associated with marginalization such as poor nutrition, reduced access to healthcare, alcohol or substance use, and chronic health conditions may interact with CHC to amplify the physiologic effects of the disease (24)(25)(26); potentially leading to an increase in symptoms such as fatigue and mild cognitive impairment, and reducing quality of life. Mental health issues, substance use, and social isolation could also impact patients' ability to cope with CHC (27,28), for example by increasing worry about the disease or increasing the level of stigma or discrimination experienced.…”

Section: Potential Causes Of Lower Health Utilities In Patients From ...mentioning

confidence: 99%

Disparities in health utilities among hepatitis C patients receiving care in different settings

Saeed

Mason²,

Mitsakakis

et al. 2023

Canadian Liver Journal

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BACKGROUND: Although chronic hepatitis C (CHC) disproportionately affects marginalized individuals, most health utility studies are conducted in hospital settings which are difficult for marginalized patients to access. We compared health utilities in CHC patients receiving care at hospital-based clinics and socio-economically marginalized CHC patients receiving care through a community-based program. METHODS: We recruited CHC patients from hospital-based clinics at the University Health Network and community-based sites of the Toronto Community Hep C Program, which provides treatment, support, and education to patients who have difficulty accessing mainstream health care. We elicited utilities using six standardized instruments (EuroQol-5D-3L [EQ-5D], Health Utilities Index Mark 2/Mark 3 [HUI2/HUI3], Short Form-6D [SF-6D], time trade-off [TTO], and Visual Analogue Scale [VAS]). Multivariate regression analysis was performed to examine factors associated with differences in health utility. RESULTS: Compared with patients recruited from the hospital setting ( n = 190), patients recruited from the community setting ( n = 101) had higher unemployment (87% versus 67%), history of injection drug use (88% versus 42%), and history of mental health issue(s) (79% versus 46%). Unadjusted health utilities were lower in community than hospital patients (eg, EQ-5D: 0.722 ± 0.209 versus 0.806 ± 0.195 [Mean ± SD]). Unemployment and a history of mental health issue(s) were significant predictors of low health utility. CONCLUSIONS: Socio-economically marginalized CHC patients have lower health utilities than patients typically represented in the CHC utility literature. Their utilities should be incorporated into future cost-utility analyses to better represent the population living with CHC in health policy decisions.

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Motivation to Quit Drinking in Individuals Coinfected with HIV and Hepatitis C

et al. 2019

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Prospective Longitudinal Substance Use Patterns in Patients Preparing for Hepatitis C Treatment

Cited by 9 publications

References 27 publications

Quality of Life, Functioning, and Coping in HCV Patients Continuing Versus Ceasing Alcohol Use

Quality of Life, Functioning, and Coping in HCV Patients Continuing Versus Ceasing Alcohol Use

Disparities in health utilities among hepatitis C patients receiving care in different settings

Motivation to Quit Drinking in Individuals Coinfected with HIV and Hepatitis C

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