Prospective memory deficits are associated with unemployment in persons living with HIV infection.

Woods, Steven Paul; Weber, Erica; Weisz, Bradley M.; Twamley, Elizabeth W.; Grant, Igor

doi:10.1037/a0022753

Cited by 78 publications

(65 citation statements)

References 51 publications

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“…(1,2,9) The Mini-Mental State Examination showed that 28.2% of older people with HIV in our study had cognitive deficit, with significant association with female sex and age 60 to 69 years; however, we found few data in the scientific literature with which to compare this result. (12,13) In the assessment of mental health/humor we found that 24.1% of elderly patients had dysthymia (mild depression); of these, most were men age 60 to 69 years. However, this result was not significant.…”

Section: Discussionmentioning

confidence: 96%

“…This result is similar to the adherence found in the literature showing that older people can guarantee significant control of syndrome manifestation and, at the same time, their longevity as HIV-positive individuals. (11)(12)(13) Effectiveness of adherence to antiretroviral therapy shows a borderline reliability of patients in relation to offering treatment as a way to improve quality of life, in addition to the significant relationship between use of antiretroviral therapy and not being affected by an opportunistic disease. (4,8,11) It is believed that despite the viral suppression provided by the antiretroviral therapy, the level of systemic persistent immune activation and inflammation is low.…”

Section: Discussionmentioning

confidence: 99%

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Limitações funcionais e incapacidades de idosos com síndrome de imunodeficiência adquirida

Cruz

Ramos

2015

Acta paul. enferm.

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Objective: To evaluate functional ability of older people with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS). Methods: This cross-sectional study using observational epidemiological inquiry collected data through interviews and from medical record of 142 older people with HIV/AIDS age 60 to 81 years. Participants were evaluated for cognitive functionality, mental health and activities of daily living domains. We conducted absolute and relative analyses of continuous variables and associations of independent variables. Results: Among the study participants, 82.39% had AIDS, 35.2% had more than 9 years of formal education, and 35% were still using cannabis. HIV was transmitted during heterosexual intercourse in 71.7% of participants and through sex with multiple partners in 70.3%. Adherence to antiretroviral therapy was satisfactory. Functional loss was significant among those age 70 years or older from both sexes. Conclusion: Functional loss of older people with HIV/AIDS did not differ from results found in the literature among the HIV-negative aging population. ResumoObjetivo: Avaliar a capacidade funcional de idosos com síndrome de imunodeficiência adquirida (HIV/AIDS). Métodos: Estudo transversal com inquérito epidemiológico observacional com a coleta de dados realizada através de entrevistas e fonte documental de 142 idosos portadores do vírus da imunodeficiência humana, entre 60 e 81 anos de idade, avaliados pelos domínios de funcionalidade cognitiva, saúde mental e Atividades da Vida Diária. Foram realizadas análise absoluta e relativa das variáveis contínuas, além da associação das variáveis independentes. Resultados: Viviam com AIDS 82,39% dos idosos da amostra; 35,2% deles tinham mais de 9 anos de estudo e 35% usavam maconha. Dentre eles, 71,7% se contaminaram em relações heterossexuais e 70,3% em relações com múltiplos parceiros. Constatou-se satisfatória a adesão à terapia antirretroviral. Foi significativa a perda funcional naqueles com 70 anos ou mais de idade de ambos os sexos. Conclusão: As perdas funcionais dos idosos portadores não foram diferentes das verificadas em outros estudos com população idosa não portadora.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Limitações funcionais e incapacidades de idosos com síndrome de imunodeficiência adquirida

Cruz

Ramos

2015

Acta paul. enferm.

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“…In terms of its ecological validity, the MIST has been significantly associated with a variety of important everyday functioning outcomes, including declines in instrumental activities of daily living (Woods, Iudicello, et al, 2008; Woods, Weinborn, Velnoweth, Rooney, & Bucks; 2012), financial mismanagement (Pirogovsky, Woods, Filoteo, & Gilbert, 2012), medication non-adherence (Woods, Moran, Carey, et al, 2008b; Woods et al, 2009), unemployment (Woods et al, 2011), and lower health-related quality of life (Doyle et al, 2012). In fact, results from the above studies suggest that the MIST accounts for variance above and beyond other important predictors like general cognitive status, depression, disease severity, and sociodemographics (e.g., Woods et al, 2009). …”

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confidence: 99%

Construct Validity of the Memory for Intentions Screening Test (MIST) in Healthy Older Adults

et al. 2014

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The Memory for Intentions Screening Test (MIST) is a clinical measure of prospective memory (PM). There is emerging support for the sensitivity and ecological relevance of the MIST in clinical populations. In the present study, the construct validity of the MIST was evaluated in 40 younger (18–30 years), 24 young-old (60–69 years), and 37 old-old (70+ years) healthy adults. Consistent with expectations derived from the PM and aging literature, older adults demonstrated lower scores on the MIST’s primary scale scores (particularly on the time-based scale), but slightly better performance on the semi-naturalistic 24-hour trial. Among the healthy older adults, the MIST showed evidence of both convergent (e.g., verbal fluency) and divergent (e.g., visuoperception) correlations with standard clinical tests, although the magnitude of those correlations were comparable across the time- and event-based scales. Together, these results support the discriminant and convergent validity of the MIST as a measure of PM in healthy older adults.

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“…In terms of its neurocognitive correlates, event-based PM deficits in HIV infection are most prevalent among persons with HIV-associated neurocognitive disorders (HAND, i.e., global neurocognitive dysfunction; Zogg et al, 2011) and are related to impairments in retrospective memory, executive functions, and information processing speed (Zogg et al, 2011). Of clinical relevance, event-based PM deficits are independently associated with higher rates of healthcare non-compliance (Zogg et al, 2010), medication non-adherence (Contardo, Black, Beauvais, Dieckhaus, & Rosen, 2009), dependence in instrumental activities of daily living (Woods et al, 2008), and unemployment (Woods et al, 2011) in HIV. As such, there is a need to understand the cognitive mechanisms of event-based PM in HIV in an effort to inform the development of effective interventions to improve PM and thus optimize real-world outcomes for persons living with HIV infection.…”

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confidence: 99%

Allowing brief delays in responding improves event-based prospective memory for young adults living with HIV disease

Loft

Doyle

Naar‐King

et al. 2014

Journal of Clinical and Experimental Neuropsychology

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Event-based prospective memory (PM) tasks require individuals to remember to perform an action when they encounter a specific cue in the environment, and have clear relevance for daily functioning for individuals with HIV. In many everyday tasks, the individual must not only maintain the intent to perform the PM task, but the PM task response also competes with the alternative and more habitual task response. The current study examined whether event-based PM can be improved by slowing down the pace of the task environment. Fifty-seven young adults living with HIV performed an ongoing lexical decision task while simultaneously performing a PM task of monitoring for a specific word (which was focal to the ongoing task of making lexical decisions) or syllable contained in a word (which was nonfocal). Participants were instructed to refrain from making task responses until after a tone was presented, which occurred at varying onsets (0–1600ms) after each stimulus appeared. Improvements in focal and non-focal PM accuracy were observed with response delays of 600ms. Furthermore, the difference in PM accuracy between the low demand focal PM task and the resource demanding non-focal PM task was reduced by half across increasingly longer delays, falling from 31% at 0ms delay to only 14% at 1600ms delay. The degree of ongoing task response slowing for the PM conditions, relative to a control condition that did not have a PM task and made lexical decisions only, also decreased with increased delay. Overall, the evidence indicates that delaying the task responses of younger HIV-infected adults increased the probability that the PM relevant features of task stimuli were adequately assessed prior to the ongoing task response, and by implication that younger HIV infected adults can more adequately achieve PM goals when the pace of the task environment is slowed down.

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Prospective memory deficits are associated with unemployment in persons living with HIV infection.

Cited by 78 publications

References 51 publications

Limitações funcionais e incapacidades de idosos com síndrome de imunodeficiência adquirida

Limitações funcionais e incapacidades de idosos com síndrome de imunodeficiência adquirida

Construct Validity of the Memory for Intentions Screening Test (MIST) in Healthy Older Adults

Allowing brief delays in responding improves event-based prospective memory for young adults living with HIV disease

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