Prospective MRI assessment for invasive lobular breast cancer. Correlation with tumour size at histopathology and influence on surgical management

Muttalib, Masoom; Ibrahem, Renan E.; Khashan, Ali S.; Hajaj, Mohamad

doi:10.1016/j.crad.2013.07.016

Cited by 18 publications

(19 citation statements)

References 16 publications

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“…Published results assessing MRI-pathology concordance ranged from an underestimation rate of 0 -59 % to an overestimation rate of 7 -70 % [3,18,23,24]. Limits within which measurements on MRI are considered concordant with measurements at pathology vary and range from 0 mm -20 mm [11,[24][25][26][27].…”

Section: Discussionmentioning

confidence: 98%

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Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

et al. 2015

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Section: Discussionmentioning

confidence: 98%

“…Various authors [8,[10][11][12][13] have proposed MRI for the preoperative assessment of ILC. Most studies addressing the accuracy of MRI for establishing the tumour extent in ILC are based on a small numbes of women, and report overestimation rates are of up to 34 % [10,11,[14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

et al. 2015

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“…However, studies have demonstrated significant variability in tumor size estimation by MRI, with underestimation reported in 8% to 59% of cases and overestimation in 11% to 70% of cases. [20][21][22][23][24] Two prospective RCTs evaluated the effect of MRI on re-operation rates (both re-excision and conversion to mastectomy) in patients deemed appropriate for BCS. 25,26 The COMICE (Comparative Effectiveness of MRI in Breast Cancer) trial multicenter collaboration included 1625 women randomized to either perioperative MRI or no additional imaging between 2002 and 2007.…”

Section: Mri and Short-term Surgical Outcomesmentioning

confidence: 99%

“…Proponents of breast MRI argue that MRI better characterizes tumor extent and, as such, should improve surgical planning and decrease the rate of positive surgical resection margins and, therefore, the need for re‐excision. However, studies have demonstrated significant variability in tumor size estimation by MRI, with underestimation reported in 8% to 59% of cases and overestimation in 11% to 70% of cases …”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging in patients with newly diagnosed breast cancer: A review of the literature

Pilewskie

King

2014

Cancer

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The use of magnetic resonance imaging (MRI) in patients with newly diagnosed breast cancer remains controversial. Here we review the current use of breast MRI and the impact of MRI on short-term surgical outcomes and rates of local recurrence. In addition, we address the use of MRI in specific patient populations, such as those with ductal carcinoma in situ, invasive lobular carcinoma, and occult primary breast cancer, and discuss the potential role of MRI for assessing response to neoadjuvant chemotherapy. Although MRI has improved sensitivity compared with conventional imaging, this has not translated into improved short-term surgical outcomes or long-term patient benefit, such as improved local control or survival, in any patient population. MRI is an important diagnostic test in the evaluation of patients presenting with occult primary breast cancer and has shown promise in monitoring response to neoadjuvant chemotherapy; however, the data do not support the routine use of perioperative MRI in patients with newly diagnosed breast cancer. Cancer 2014;120:2080-9. V C 2014 American Cancer Society.KEYWORDS: magnetic resonance imaging (MRI), breast cancer, breast-conserving surgery, local recurrence. INTRODUCTIONThe use of magnetic resonance imaging (MRI) in patients with newly diagnosed breast cancer requires balancing the positive and negative aspects of additional imaging and, as evidenced by the growing number of editorials and reviews arguing for or against the routine use of MRI, 1-8 remains an area of significant controversy. This debate has been fueled by inconsistent data largely comprised of small, single-institution retrospective studies, although 2 randomized controlled trials (RCTs) and several meta-analyses have provided more robust data evaluating MRI in the perioperative setting. The "pros" of perioperative MRI include improved sensitivity compared with conventional imaging and therefore increased identification of multifocal, multicentric, or contralateral disease. With improved sensitivity comes a theoretical improvement in short-term surgical management and/or long-term outcomes. The "cons" of perioperative MRI include the high falsepositive rate, potential treatment delays, increased mastectomy rates and cost, and, some argue, overdiagnosis and overtreatment of MRI-only detected disease. Here we review the relevant data regarding MRI use in patients with newly diagnosed breast cancer, examining both the short-term and long-term outcomes, MRI use in populations of women with ductal carcinoma in situ (DCIS) and invasive lobular carcinoma (ILC), MRI's role in patients presenting with occult primary breast cancer, and MRI's ability to evaluate neoadjuvant chemotherapy (NAC) response.

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“…MRI has not been shown to improve local recurrence rates, re-excision rates, or survival outcomes. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] Preoperative MRI delays time from diagnosis to surgery. 15 Furthermore, MRI findings have upgraded surgery from breast conservation to mastectomy.…”

Section: Introductionmentioning

confidence: 99%

Clinical accuracy of preoperative breast MRI for breast cancer

Tseng

Kyrillos

Liederbach

et al. 2017

Journal of Surgical Oncology

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Prospective MRI assessment for invasive lobular breast cancer. Correlation with tumour size at histopathology and influence on surgical management

Cited by 18 publications

References 16 publications

Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

Which factors influence MRI-pathology concordance of tumour size measurements in breast cancer?

Magnetic resonance imaging in patients with newly diagnosed breast cancer: A review of the literature

Clinical accuracy of preoperative breast MRI for breast cancer

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