Prospective multicenter assessment of the impact of EUS-guided gastroenterostomy on patient quality of life in unresectable malignant gastric outlet obstruction

García‐Alonso, Francisco Javier; Chavarría, Carlos; Subtil, Juan Carlos; Aparicio, José Ramón; Bea, Victoria Busto; Martinez-Moreno, Belén.; Vila, Juan J.; Martín-Álvarez, Vanessa; Sanchez-Delgado, Laura; Serna-Higuera, Carlos de la; Pérez-Miranda, Manuel

doi:10.1016/j.gie.2023.02.015

Cited by 12 publications

(3 citation statements)

References 27 publications

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“…Treatment with EUS-GE led to a significantly lower 6-month reintervention rate (4% vs. 29% with both reinterventions in the EUS-GE arm occurring in subjects who had actually received a duodenal stent in an intention-to-treat analysis) compared to duodenal stenting. EUS-GE was also associated with longer stent patency (HR: 0.13, 95% CI 0.08-0.22) and improved A prospective multicenter study (n = 64, 35.9% PDAC, all unresectable) from Spain found a 98.5% technical success rate in performing EUS-GE with 75.4% of patients able to eat 7 days post-procedure [39]. Furthermore, at 30 days post-procedure, 84.4% of patients tolerated a diet with investigators finding a significant improvement in quality of life at this time point.…”

Section: Eus-guided Gastroenterostomymentioning

confidence: 97%

“…A prospective multicenter study ( n = 64, 35.9% PDAC, all unresectable) from Spain found a 98.5% technical success rate in performing EUS-GE with 75.4% of patients able to eat 7 days post-procedure [ 39 ]. Furthermore, at 30 days post-procedure, 84.4% of patients tolerated a diet with investigators finding a significant improvement in quality of life at this time point.…”

Section: Eus-based Treatment Modalitiesmentioning

confidence: 99%

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Therapeutic Endoscopic Ultrasound for Complications of Pancreatic Cancer

Han,

Papachristou

2023

Cancers

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Progression of pancreatic adenocarcinoma can result in disease complications such as biliary obstruction and gastric outlet obstruction. The recent advances in endoscopic ultrasound (EUS) have transformed EUS from a purely diagnostic technology to a therapeutic modality, particularly with the development of lumen-apposing metal stents. In terms of biliary drainage, EUS-guided choledochoduodenostomy and EUS-guided hepaticogastrostomy offer safe and effective techniques when conventional transpapillary stent placement via ERCP fails or is not possible. If these modalities are not feasible, EUS-guided gallbladder drainage offers yet another salvage technique when the cystic duct is non-involved by the cancer. Lastly, EUS-guided gastroenterostomy allows for an effective bypass treatment for cases of gastric outlet obstruction that enables patients to resume eating within several days. Future randomized studies comparing these techniques to current standard-of-care options are warranted to firmly establish therapeutic EUS procedures within the treatment algorithm for this challenging disease.

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Section: Eus-guided Gastroenterostomymentioning

confidence: 97%

Section: Eus-based Treatment Modalitiesmentioning

confidence: 99%