P Pu ur rp po os se e: : To determine whether the use of cell salvage reduces the proportion of patients receiving at least one unit of allogeneic packed red blood cells during the perioperative period of an elective vascular surgery.S So ou ur rc ce e: : We identified all relevant articles through the combined use of electronic searches of the MEDLINE and EMBASE databases, the Cochrane library as well as hand searching of all randomized clinical trials and review articles. The electronic search included articles published between 1966 and April 2001. The search included textword searches using "autotransfusion," "cell salvage," "device," or Medical Subject Headings "autologous blood transfusion" or a "randomized controlled trials" filter. P Pr ri in nc ci ip pa al l f fi in nd di in ng gs s: : Five randomized controlled trials (RCT) were identified involving cell salvage and vascular surgeries. In infra renal abdominal aortic aneurysm surgery the risk ratio (the risk of receiving at least one unit of allogeneic red cells) was 0.37 [95% confidence intervals (CI) of 0.06 to 2.36]. In elective aorto-femoral bypass surgery the risk ratio was 0.97 (95% CI of 0.66 to 1.42). The pooled risk ratio for cell salvage in vascular surgery was 0.67 (95% CI of 0.35 to 1.28).C Co on nc cl lu us si io on n: : Cell salvage, a commonly used technique to recover red cells from the operative field, has been the subject of several studies in vascular surgery. There is insufficient evidence to recommend the routine use of cell salvage in elective abdominal aortic aneurysm and aorto-femoral bypass surgeries. A large RCT would elucidate whether cell salvage is effective as a blood conservation technique. de 0,97 (IC de 95 % de 0,66 à 1,42). Le risque commun en chirurgie vasculaire était de 0,67 (IC de 95 % de 0,35 à 1,28
Objectif
Source : Les articles pertinents ont été repérés par des recherches électroniques combinées dans MEDLINE et EMBASE, la bibliothèque Cochrane et une recherche manuelle des essais cliniques randomisés et des exposés de synthèse. La recherche électronique comprend des articles publiés entre 1966 et avril 2001 à partir des termes «autotransfusion», «cell salvage», «device» ou de mots clés du domaine médical comme «autologous blood transfusion» ou d'un filtre sur les «randomized controlled trials».
Constatations principales : Nous avons trouvé cinq études randomisées et contrôlées (ERC