Introduction: Massive tear of the rotator cuff (DMMR) is a degenerative clinical condition, which corresponds to a 5 cm rupture, or one that compromises two or more tendons of the rotator cuff (MR), generating loss of functionality and disabling pain.Objective: To describe changes in pain and shoulder function following a 6-week program of lateral-imaging and motion imaging therapy and selective glenohumeral activation exercises in subjects with massive rotator cuff tears.Methods: This study is a descriptive research and design of a series of cases, with a sample of 50 participants with diagnosis of rotator cuff mastication. Patients underwent a glenohumeral selective exercise program plus laterality and motion imaging therapy for 6 weeks. The variables of function, pain, abduction ROM and shoulder flexion were measured at sixth week and sixth month of evolution.Results: There were significant differences in pain intensity, shoulder function, AROM flexion and shoulder abduction AROM, after the intervention (p > 0.05). Statistically significant differences were found for all outcome measures between the intervention and the sixth follow-up month (p < 0.05). Only the